[HTML][HTML] P4HA1 regulates human colorectal cancer cells through HIF1α‑mediated Wnt signaling
Q Zhang, Y Yin, H Zhao, Y Shi, W Zhang… - Oncology …, 2021 - spandidos-publications.com
Colorectal cancer (CRC) is the third most commonly diagnosed malignancy that is
associated with high levels of mortality. CRCs are often associated with an aberrant …
associated with high levels of mortality. CRCs are often associated with an aberrant …
[HTML][HTML] Understanding the matrix: collagen modifications in tumors and their implications for immunotherapy
R Borst, L Meyaard, MI Pascoal Ramos - Journal of Translational …, 2024 - Springer
Tumors are highly complex and heterogenous ecosystems where malignant cells interact
with healthy cells and the surrounding extracellular matrix (ECM). Solid tumors contain large …
with healthy cells and the surrounding extracellular matrix (ECM). Solid tumors contain large …
P4HA2 promotes tumor progression and is transcriptionally regulated by SP1 in colorectal cancer
X Dang, X Chen, Z Liang, Z Dai, W Ding… - Cancer Biology & …, 2024 - Taylor & Francis
ABSTRACT P4HA2 has been implicated in various malignant tumors; however, its
expression and functional role in colorectal cancer (CRC) remain poorly elucidated. This …
expression and functional role in colorectal cancer (CRC) remain poorly elucidated. This …
Multilevel chitosan–gelatin particles loaded with P4HA1 siRNA suppress glioma development
Y Zhou, J Tian, Y Zhu, Y Zhang, X Zhao - Drug Delivery and Translational …, 2024 - Springer
It has been reported that prolyl 4-hydroxylase subunit alpha 1 (P4HA1) promoted tumor
growth and metastasis of glioma; thus, targeting P4HA1 may be a promising therapeutic …
growth and metastasis of glioma; thus, targeting P4HA1 may be a promising therapeutic …
The extracellular matrix landscape in salivary gland carcinomas is defined by cellular differentiation via expression of three distinct protein modules
C Arolt, F Hoffmann, L Nachtsheim… - The Journal of …, 2023 - Wiley Online Library
The extracellular matrix (ECM) is an integral part of the tumor microenvironment of
carcinomas. Even though salivary gland carcinomas (SGCs) display a range of tumor cell …
carcinomas. Even though salivary gland carcinomas (SGCs) display a range of tumor cell …
P4HA1 Promotes Cell Migration and Colonization in Hypopharyngeal Squamous Cell Carcinoma
K Sato, D Sano, H Takahashi, T Kuwahara… - Anticancer …, 2023 - ar.iiarjournals.org
Background/Aim: This study aimed to identify key molecules associated with the survival of
patients with hypopharyngeal squamous cell carcinoma (HpSCC) by combining in silico and …
patients with hypopharyngeal squamous cell carcinoma (HpSCC) by combining in silico and …
Development of cancer prognostic signature based on pan-cancer proteomics
W Huang, J Chen, W Weng, Y Xiang, H Shi… - …, 2020 - Taylor & Francis
Utilizing genomic data to predict cancer prognosis was insufficient. Proteomics can improve
our understanding of the etiology and progression of cancer and improve the assessment of …
our understanding of the etiology and progression of cancer and improve the assessment of …
Comprehensive Analysis of Gene Expression Profiles Identifies a P4HA1-Related Gene Panel as a Prognostic Model in Colorectal Cancer Patients
Z Chen, M Chen, Z Xue, X Zhu - Cancer Biotherapy & …, 2021 - liebertpub.com
Objective: Colorectal cancer (CRC) is the leading cause of mortality worldwide. Growing
evidence suggests that the current pathological staging system is inadequate for efficient …
evidence suggests that the current pathological staging system is inadequate for efficient …
[HTML][HTML] P4HA1 expression and function in esophageal squamous cell carcinoma
W Gou, B Song, Y Yang - Medicine, 2023 - journals.lww.com
This study aimed to explore the effect of P4HA1 (prolyl 4-hydroxylase subunit α1) and its
ratio on the prognosis of esophageal squamous cell carcinoma. The expression data of …
ratio on the prognosis of esophageal squamous cell carcinoma. The expression data of …