Tranexamic acid–an old drug still going strong and making a revival

L Tengborn, M Blombäck, E Berntorp - Thrombosis research, 2015 - Elsevier
Experience with tranexamic acid, an indirect fibrinolytic inhibitor, started as soon as it was
released from Shosuke Okamoto's lab in the early 1960s. It was first prescribed to females …

Tranexamic acid evidence and controversies: an illustrated review

N Relke, NLJ Chornenki… - Research and practice in …, 2021 - Wiley Online Library
Tranexamic acid (TXA) is an antifibrinolytic agent commonly used for the treatment or
prevention of bleeding. Indications for TXA are diverse, including heavy menstrual bleeding …

International consensus statement on the diagnosis and management of autosomal dominant polycystic kidney disease in children and young people

C Gimpel, C Bergmann, D Bockenhauer… - Nature Reviews …, 2019 - nature.com
These recommendations were systematically developed on behalf of the Network for Early
Onset Cystic Kidney Disease (NEOCYST) by an international group of experts in autosomal …

Total kidney volume in autosomal dominant polycystic kidney disease: a biomarker of disease progression and therapeutic efficacy

A Alam, NK Dahl, JH Lipschutz, S Rossetti… - American Journal of …, 2015 - Elsevier
Autosomal dominant polycystic kidney disease (ADPKD) is the most common potentially life-
threatening monogenic disorder in humans, characterized by progressive development and …

Evidence-based clinical practice guidelines for polycystic kidney disease 2014

S Horie, T Mochizuki, S Muto, K Hanaoka… - Clinical and …, 2016 - Springer
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary
kidney disease, with approximately half of the patients experiencing end-stage renal …

[HTML][HTML] Documento de consenso de poliquistosis renal autosómica dominante del grupo de trabajo de enfermedades hereditarias de la Sociedad Española de …

E Ars, C Bernis, G Fraga, M Furlano, V Martínez… - nefrologia, 2022 - Elsevier
La poliquistosis renal autosómica dominante (PQRAD) es la causa más frecuente de
nefropatía genética y representa entre el 6 y el 10% de los pacientes en terapia de …

Effect of tranexamic acid on gross hematuria: A pilot randomized clinical trial study

P Moharamzadeh, S Ojaghihaghighi, M Amjadi… - The American journal of …, 2017 - Elsevier
Objective Local forms of the tranexamic acid have been effective in treating many
haemorrhagic cases. So that the aim of the current study is to assess the effectiveness of …

Systematic review of hematuria and acute renal failure with tranexamic acid

SG Lee, J Fralick, CJD Wallis, M Boctor… - European Journal of …, 2022 - Wiley Online Library
Objectives To conduct a systematic review of tranexamic acid (TXA) and the risk of renal
failure from urinary clots in adult patients with hematuria. Methods A systematic review of …

Manifestation of tranexamic acid toxicity in chronic kidney disease and kidney transplant patients: a report of four cases and review of literature

TKW Ma, KM Chow, BCH Kwan, CB Leung… - …, 2017 - Wiley Online Library
Aim Tranexamic acid (TXA) is a synthetic anti‐fibrinolytic agent commonly used for the
prevention and treatment of bleeding disorders. The aim of this study is to describe the …

[HTML][HTML] Consensus document on autosomal dominant polycystic kindey disease from the Spanish Working Group on Inherited Kindey Diseases. Review 2020

E Ars, C Bernis, G Fraga, M Furlano, V Martínez… - Nefrología (English …, 2022 - Elsevier
Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent cause of
genetic renal disease and accounts for 6–10% of patients on kidney replacement therapy …