COVID-19 and the vasculature: current aspects and long-term consequences

B Martinez-Salazar, M Holwerda, C Stuedle… - Frontiers in cell and …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was first identified in
December 2019 as a novel respiratory pathogen and is the causative agent of Corona Virus …

Dyspnea in post-COVID syndrome following mild acute COVID-19 infections: potential causes and consequences for a therapeutic approach

KJ Wirth, C Scheibenbogen - Medicina, 2022 - mdpi.com
Dyspnea, shortness of breath, and chest pain are frequent symptoms of post-COVID
syndrome (PCS). These symptoms are unrelated to organ damage in most patients after …

How does COVID-19 affect the heart?

LR Sewanan, KJ Clerkin, NR Tucker… - Current Cardiology Reports, 2023 - Springer
Abstract Purpose of Review Cardiac consequences occur in both acute COVID-19 and post-
acute sequelae of COVID-19 (PASC). Here, we highlight the current understanding about …

Prevalence of acute pulmonary embolism at autopsy in patients with COVID-19

M Zuin, MM Engelen, C Bilato, T Vanassche… - The American Journal of …, 2022 - Elsevier
To date, the actual prevalence of acute pulmonary embolism (PE) in patients with SARS-
CoV-2 infection remains unknown, as systematic screening for PE is cumbersome. We …

COVID-19 pathology in the lung, kidney, heart and brain: the different roles of T-cells, macrophages, and microthrombosis

TE Poloni, M Moretti, V Medici, E Turturici, G Belli… - Cells, 2022 - mdpi.com
Here, we aim to describe COVID-19 pathology across different tissues to clarify the disease's
pathophysiology. Lungs, kidneys, hearts, and brains from nine COVID-19 autopsies were …

Highly efficient SARS-CoV-2 infection of human cardiomyocytes: spike protein-mediated cell fusion and its inhibition

CK Navaratnarajah, DR Pease, PJ Halfmann… - Journal of …, 2021 - Am Soc Microbiol
Severe cardiovascular complications can occur in coronavirus disease of 2019 (COVID-19)
patients. Cardiac damage is attributed mostly to the aberrant host response to acute …

Myocarditis associated with COVID-19 and its vaccines-a systematic review

A Rout, S Suri, M Vorla, DK Kalra - Progress in Cardiovascular Diseases, 2022 - Elsevier
Since the beginning of the COVID-19 (Coronavirus Disease of 2019) pandemic, myocarditis
has received much attention and controversy as one of the more worrisome cardiovascular …

Human cardiac organoids to model COVID‐19 cytokine storm induced cardiac injuries

DC Arhontoulis, CM Kerr, D Richards… - Journal of Tissue …, 2022 - Wiley Online Library
Acute cardiac injuries occur in 20%–25% of hospitalized COVID‐19 patients. Herein, we
demonstrate that human cardiac organoids (hCOs) are a viable platform to model the …

[HTML][HTML] Insights into the role of neutrophils and neutrophil extracellular traps in causing cardiovascular complications in patients with COVID-19: a systematic review

F Nappi, F Bellomo, SS Avtaar Singh - Journal of Clinical Medicine, 2022 - mdpi.com
Background: The coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-
CoV-2 virus has resulted in significant mortality and burdening of healthcare resources …

From cytokine storm to cytokine breeze: did lessons learned from immunopathogenesis improve immunomodulatory treatment of moderate-to-severe COVID-19?

G Rondovic, D Djordjevic, I Udovicic, I Stanojevic… - Biomedicines, 2022 - mdpi.com
Complex immune response to infection has been highlighted, more than ever, during the
COVID-19 pandemic. This review explores the immunomodulatory treatment of moderate-to …