Epigenome in early mammalian development: inheritance, reprogramming and establishment
Q Xu, W Xie - Trends in cell biology, 2018 - cell.com
Drastic epigenetic reprogramming takes place during preimplantation development, leading
to the conversion of terminally differentiated gametes to a totipotent embryo. Deficiencies in …
to the conversion of terminally differentiated gametes to a totipotent embryo. Deficiencies in …
In vivo oxygen, temperature and pH dynamics in the female reproductive tract and their importance in human conception: a systematic review
BACKGROUND Despite advances in ART, implantation and pregnancy rates per embryo
transfer still remain low. IVF laboratories strive to ensure that the process of handling …
transfer still remain low. IVF laboratories strive to ensure that the process of handling …
Role of DNA methylation in imprinting disorders: an updated review
AR Elhamamsy - Journal of Assisted Reproduction and Genetics, 2017 - Springer
Genomic imprinting is a complex epigenetic process that contributes substantially to
embryogenesis, reproduction, and gametogenesis. Only small fraction of genes within the …
embryogenesis, reproduction, and gametogenesis. Only small fraction of genes within the …
Mitochondria in early development: linking the microenvironment, metabolism and the epigenome
AJ Harvey - Reproduction, 2019 - rep.bioscientifica.com
Mitochondria, originally of bacterial origin, are highly dynamic organelles that have evolved
a symbiotic relationship within eukaryotic cells. Mitochondria undergo dynamic, stage …
a symbiotic relationship within eukaryotic cells. Mitochondria undergo dynamic, stage …
Effects of embryo-derived exosomes on the development of bovine cloned embryos
P Qu, S Qing, R Liu, H Qin, W Wang, F Qiao, H Ge… - PloS one, 2017 - journals.plos.org
The developmental competence of in vitro cultured (IVC) embryos is markedly lower than
that of their in vivo counterparts, suggesting the need for optimization of IVC protocols …
that of their in vivo counterparts, suggesting the need for optimization of IVC protocols …
Contemporary use of ICSI and epigenetic risks to future generations
R Sciorio, SC Esteves - Journal of Clinical Medicine, 2022 - mdpi.com
Since the birth of Louise Brown in 1978 via IVF, reproductive specialists have acquired
enormous knowledge and refined several procedures, which are nowadays applied in …
enormous knowledge and refined several procedures, which are nowadays applied in …
Epigenetic risks of medically assisted reproduction
R Sciorio, N El Hajj - Journal of Clinical Medicine, 2022 - mdpi.com
Since the birth of Louise Joy Brown, the first baby conceived via in vitro fertilization, more
than 9 million children have been born worldwide using assisted reproductive technologies …
than 9 million children have been born worldwide using assisted reproductive technologies …
Environmentally induced epigenetic toxicity: potential public health concerns
EL Marczylo, MN Jacobs, TW Gant - Critical reviews in toxicology, 2016 - Taylor & Francis
Throughout our lives, epigenetic processes shape our development and enable us to adapt
to a constantly changing environment. Identifying and understanding environmentally …
to a constantly changing environment. Identifying and understanding environmentally …
Embryo culture at a reduced oxygen concentration of 5%: a mini review
R Sciorio, GD Smith - Zygote, 2019 - cambridge.org
The optimum oxygen tension for culturing mammalian embryos has been widely debated by
the scientific community. While several laboratories have moved to using 5% as the value for …
the scientific community. While several laboratories have moved to using 5% as the value for …
Pluripotent stem cell metabolism and mitochondria: beyond ATP
Metabolism is central to embryonic stem cell (ESC) pluripotency and differentiation, with
distinct profiles apparent under different nutrient milieu, and conditions that maintain …
distinct profiles apparent under different nutrient milieu, and conditions that maintain …