Recent advances in contrast-enhanced photoacoustic imaging: overcoming the physical and practical challenges

W Choi, B Park, S Choi, D Oh, J Kim, C Kim - Chemical Reviews, 2023 - ACS Publications
For decades now, photoacoustic imaging (PAI) has been investigated to realize its potential
as a niche biomedical imaging modality. Despite its highly desirable optical contrast and …

Molecular probes for autofluorescence-free optical imaging

Y Jiang, K Pu - Chemical reviews, 2021 - ACS Publications
Optical imaging is an indispensable tool in clinical diagnostics and fundamental biomedical
research. Autofluorescence-free optical imaging, which eliminates real-time optical …

Chemical design of activatable photoacoustic probes for precise biomedical applications

Y Liu, L Teng, B Yin, H Meng, X Yin, S Huan… - Chemical …, 2022 - ACS Publications
Photoacoustic (PA) imaging technology, a three-dimensional hybrid imaging modality that
integrates the advantage of optical and acoustic imaging, has great application prospects in …

Bioapplications of small molecule Aza-BODIPY: from rational structural design to in vivo investigations

Z Shi, X Han, W Hu, H Bai, B Peng, L Ji, Q Fan… - Chemical Society …, 2020 - pubs.rsc.org
Boron-dipyrromethene (BODIPY) belongs to a family of organoboron compounds,
commercialized as fluorescent dyes by Invitrogen™. As BODIPY derivatives, Aza-boron …

Activatable molecular probes for second near‐infrared fluorescence, chemiluminescence, and photoacoustic imaging

J Huang, K Pu - Angewandte Chemie International Edition, 2020 - Wiley Online Library
Optical imaging plays a crucial role in biomedicine. However, due to strong light scattering
and autofluorescence in biological tissue between 650–900 nm, conventional optical …

Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer

Y Liu, P Bhattarai, Z Dai, X Chen - Chemical Society Reviews, 2019 - pubs.rsc.org
The nonradiative conversion of light energy into heat (photothermal therapy, PTT) or sound
energy (photoacoustic imaging, PAI) has been intensively investigated for the treatment and …

Development of organic semiconducting materials for deep-tissue optical imaging, phototherapy and photoactivation

J Li, K Pu - Chemical Society Reviews, 2019 - pubs.rsc.org
Biophotonics as a highly interdisciplinary frontier often requires the assistance of optical
agents to control the light pathways in cells, tissues and living organisms for specific …

Ratiometric optical nanoprobes enable accurate molecular detection and imaging

X Huang, J Song, BC Yung, X Huang… - Chemical Society …, 2018 - pubs.rsc.org
Exploring and understanding biological and pathological changes are of great significance
for early diagnosis and therapy of diseases. Optical sensing and imaging approaches have …

Activatable multimodal probes for in vivo imaging and theranostics

Y Wang, Y Hu, D Ye - Angewandte Chemie, 2022 - Wiley Online Library
Multimodal imaging, which harnesses two or more imaging modalities to produce
complementary anatomical and molecular information of a living subject, has become as a …

Organic semiconducting agents for deep‐tissue molecular imaging: second near‐infrared fluorescence, self‐luminescence, and photoacoustics

Q Miao, K Pu - Advanced materials, 2018 - Wiley Online Library
Optical imaging has played a pivotal role in biology and medicine, but it faces challenges of
relatively low tissue penetration and poor signal‐to‐background ratio due to light scattering …