Metastasis accounts for the vast majority of cancer deaths. The unique challenges for
treating metastases include their small size, high multiplicity and dispersion to diverse organ …

Polymersomes are stable vesicles prepared from amphiphilic polymers and are more stable
compared with liposomes. Although these nanovesicles have many attractive properties for …

An international panel of multidisciplinary experts convened to develop recommendations
for the management of patients with liver metastases from colorectal cancer (CRC). The aim …

Tumor hypoxia is correlated with increased resistance to chemotherapy and poor overall
prognoses across a number of cancer types. We present here a cancer cell-selective and …

Fluorouracil (5-FU) is a broad spectrum cytotoxic agent being used in chemotherapy of
malignancies. However, 5-FU shows a number of limitations like short half-life, non-selective …

Folate is a B vitamin necessary for basic biological functions, including rapid cell turnover
occurring in cancer cell proliferation. Though the role of folate as a causative versus …

Oxaliplatin is being used in different malignancies and several side effects are reported for
patients taking Oxaliplatin, including peripheral neuropathy, nausea and vomiting, diarrhea …

Folate receptor alpha (FRA) is a cell surface protein whose aberrant expression in malignant
cells has resulted in its pursuit as a therapeutic target and marker for diagnosis of cancer …

Colorectal cancer (CRC) is a common cause of cancer and cancer-related death. Surgery is
the only curative modality. Fluorescence-enhanced visualization of CRC with targeted …

Targeted radionuclide therapy is based on systemic application of particle-emitting
radiopharmaceuticals which are directed toward a specific tumor-associated target …