Feeding, which is essential for all animals, is regulated by homeostatic mechanisms. In
addition, food consumption is temporally coordinated by the brain over the circadian (~ 24 h) …

Simple Summary Our daily life follows 24-h cycles in various biological functions, such as
sleep–wake and feeding/fasting cycles. These rhythms are regulated by endogenous clocks …

Mitochondrial fission-fusion dynamics and mitochondrial bioenergetics, including oxidative
phosphorylation and generation of ATP, are strongly clock controlled. Here we show that …

Metformin is a first-line drug in the treatment of type-2 diabetes mellitus (T2DM). In addition
to its antigluconeogenic and insulin-sensitizing properties, metformin has emerged as a …

Cellular homeostasis is controlled by an evolutionary conserved cellular digestive process
called autophagy. This mechanism is tightly regulated by the two sensor elements called …

Abstract Plant SNF1-Related Kinase1 (SnRK1) is an evolutionarily conserved energy-
sensing protein kinase that orchestrates transcriptional networks to maintain cellular energy …

A plethora of physiological processes show stable and synchronized daily oscillations that
are either driven or modulated by biological clocks. A circadian pacemaker located in the …

Background: Autophagy has been demonstrated to be vital for kidney homeostasis and is
centrally implicated in the pathogenesis of cisplatin-induced acute kidney injury (AKI) …

Under natural conditions, many aspects of the abiotic and biotic environment vary with time
of day, season or even era, while these conditions are typically kept constant in laboratory …

Circadian rhythms are 24-h oscillations present in most eukaryotes and many prokaryotes
that synchronize activity to the day-night cycle. They are an essential feature of organismal …