Phagocytosis is a fundamental process of cells to capture and ingest foreign particles. Small
unicellular organisms such as free-living amoeba use this process to acquire food. In …

Cryptococcus neoformans and Cryptococcus gattii are the two etiologic agents of
cryptococcosis. They belong to the phylum Basidiomycota and can be readily distinguished …

Basidiomycota (basidiomycetes) make up 32% of the described fungi and include most
wood-decaying species, as well as pathogens and mutualistic symbionts. Wood-decaying …

DAF-16, the only forkhead box transcription factors class O (FoxO) homolog in
Caenorhabditis elegans, integrates signals from upstream pathways to elicit transcriptional …

Background Fungi are among the most abundant and diverse organisms on Earth. However,
a substantial amount of the species diversity, relationships, habitats, and life strategies of …

Cryptococcus neoformans is generally considered to be an opportunistic fungal pathogen
because of its tendency to infect immunocompromised individuals, particularly those …

The frequency of severe systemic fungal diseases has increased in the last few decades.
The clinical use of antibacterial drugs, immunosuppressive agents after organ …

The importance of the Basidiomycete Cryptococcus neoformans to human health has
stimulated its development as an experimental model for both basic physiology and …

Cryptococcus neoformans is a facultative intracellular pathogen. The most distinctive feature
of C. neoformans is a polysaccharide capsule that enlarges depending on environmental …

The pathogenic fungus Cryptococcus neoformans exhibits morphological changes in cell
size during lung infection, producing both typical size 5 to 7 μm cells and large titan cells (> …