[HTML][HTML] Total neoadjuvant therapy in rectal cancer: the evidence and expectations
B Ludmila, N Alena, S Jaromir, L Radka - Critical Reviews in Oncology …, 2023 - Elsevier
Current management of locally advanced rectal cancer achieves high cure rates, distant
metastatic spread being the main cause of patients' death. Total neoadjuvant therapy (TNT) …
metastatic spread being the main cause of patients' death. Total neoadjuvant therapy (TNT) …
Evolving Standards of Care in the Management of Localized Colorectal Cancer
The treatment of patients with localized rectal cancer is complex and requires input from a
multidisciplinary team. Baseline local staging and mismatch repair protein testing are vital to …
multidisciplinary team. Baseline local staging and mismatch repair protein testing are vital to …
Factors Associated With Racial and Ethnic Disparities in Locally Advanced Rectal Cancer Outcomes
RM Shulman, M Deng, EA Handorf, JE Meyer… - JAMA Network …, 2024 - jamanetwork.com
Importance Hispanic and non-Hispanic Black patients receiving neoadjuvant therapy and
surgery for locally advanced rectal cancer (LARC) achieve less favorable clinical outcomes …
surgery for locally advanced rectal cancer (LARC) achieve less favorable clinical outcomes …
[HTML][HTML] The role of total neoadjuvant therapy in locally advanced rectal cancer: a survey of specialists attending the All-Ireland Colorectal Cancer Conference 2022 …
Background The treatment of locally advanced rectal cancer (LARC) has evolved following
recent landmark trials of total neoadjuvant therapy (TNT)—the delivery of preoperative …
recent landmark trials of total neoadjuvant therapy (TNT)—the delivery of preoperative …
Enhancing Chemotherapy Response Prediction via Matched Colorectal Tumor-Organoid Gene Expression Analysis and Network-Based Biomarker Selection
W Zhang, C Wu, H Huang, P Bleu, W Zambare… - medRxiv, 2024 - medrxiv.org
Colorectal cancer (CRC) poses significant challenges in chemotherapy response prediction
due to its molecular heterogeneity. This study introduces an innovative methodology that …
due to its molecular heterogeneity. This study introduces an innovative methodology that …
Short course radiotherapy versus radiochemotherapy for locally advanced rectal cancers in the elderly (UNICANCER PRODIGE 42/GERICO 12 study): Quality of life …
E François, N Magné, R Boulahssass… - Radiotherapy and …, 2024 - Elsevier
Background The results of the PRODIGE 42/GERICO 12 study showed that short course
radiotherapy had a better tolerance profile than radiochemotherapy, with comparable …
radiotherapy had a better tolerance profile than radiochemotherapy, with comparable …
Total neoadjuvant therapy with mFOLFIRINOX versus preoperative chemoradiotherapy in patients with locally advanced rectal cancer: long-term results of the …
T Conroy, F Castan, PL Etienne, E Rio… - Annals of …, 2024 - Elsevier
Background The standard of care for the treatment of locally advanced rectal cancer results
in an excellent local disease control but the metastasis rates remain high. PRODIGE 23 …
in an excellent local disease control but the metastasis rates remain high. PRODIGE 23 …
Total Neoadjuvant Therapy (TNT) in Rectal Cancer; Where Now, Where Next?
S Bedrikovetski, T Sammour - Coloproctology: A Practical Guide, 2024 - Springer
In this chapter, we summarize the key findings of pivotal RCTs on TNT for patients with
Locally Advanced Rectal Cancer (LARC) and discuss future directions of TNT including …
Locally Advanced Rectal Cancer (LARC) and discuss future directions of TNT including …