Coronavirus disease 2019 (COVID-19), due to infection by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is now causing a global pandemic. Aerosol …

Central nervous system (CNS) disorders (eg, multiple sclerosis, Alzheimer's disease, etc.)
represent a growing public health issue, primarily due to the increased life expectancy and …

Although ambient particulate matter or particles have been found to be associated with
morbidity and mortality all over the world, specific health effects of particles from different …

Objective: Exposure to airborne particulate matter (PM) is estimated to cause millions of
premature deaths annually. This work conveys known routes of exposure to PM and …

The alveolar epithelium of the lung is by far the most permeable epithelial barrier of the
human body. The risk for adverse effects by inhaled nanoparticles (NPs) depends on their …

Modern strategies in drug development employ in silico techniques in the design of
compounds as well as estimations of pharmacokinetics, pharmacodynamics and toxicity …

Introduction: Respiratory drug delivery is a surprisingly complex process with a number of
physical and biological challenges. Computational fluid dynamics (CFD) is a scientific …

Effective evaluation and prediction of aerosol transport deposition in the human respiratory
tracts are critical to aerosol drug delivery and evaluation of inhalation products …

The dynamics of respiratory airflows and the associated transport mechanisms of inhaled
aerosols characteristic of the deep regions of the lungs are of broad interest in assessing …

Regional deposition effects are important in the pulmonary delivery of drugs intended for the
topical treatment of respiratory ailments. They also play a critical role in the systemic delivery …