[HTML][HTML] Mechanism of bile acid-induced programmed cell death and drug discovery against cancer: A review

JY Jang, E Im, YH Choi, ND Kim - International Journal of Molecular …, 2022 - mdpi.com
Bile acids are major signaling molecules that play a significant role as emulsifiers in the
digestion and absorption of dietary lipids. Bile acids are amphiphilic molecules produced by …

[HTML][HTML] Early activation of cellular stress and death pathways caused by cytoplasmic TDP-43 in the rNLS8 mouse model of ALS and FTD

W Luan, AL Wright, H Brown-Wright, S Le… - Molecular …, 2023 - nature.com
Abstract TAR DNA binding protein 43 (TDP-43) pathology is a key feature of over 95% of
amyotrophic lateral sclerosis (ALS) and nearly half of frontotemporal dementia (FTD) cases …

Huperzine A injection ameliorates motor and cognitive abnormalities via regulating multiple pathways in a murine model of Parkinson's disease

X Guo, Y Wu, Q Wang, J Zhang, X Sheng… - European journal of …, 2023 - Elsevier
As a common progressive neurodegenerative disorder, the satisfied therapies for
Parkinson's disease (PD) are still unavailable. As a natural acetylcholinesterase inhibitor …

Therapeutic potential of nanomedicine in management of Alzheimer's disease and glioma

F Anwar, FA Al-Abbasi, S Naqvi… - International Journal …, 2023 - Taylor & Francis
Abstract Neoplasm (Glioblastoma) and Alzheimer's disease (AD) comprise two of the most
chronic psychological ailments. Glioblastoma is one of the aggressive and prevalent …

[HTML][HTML] Super-resolution microscopies, technological breakthrough to decipher mitochondrial structure and dynamic.

P Teixeira, R Galland, A Chevrollier - Seminars in Cell & Developmental …, 2024 - Elsevier
Mitochondria are complex organelles with an outer membrane enveloping a second inner
membrane that creates a vast matrix space partitioned by pockets or cristae that join the …

[HTML][HTML] Widespread selenium deficiency in the brain of cases with Huntington's disease presents a new potential therapeutic target

M Scholefield, S Patassini, J Xu, GJS Cooper - EBioMedicine, 2023 - thelancet.com
Summary Background Huntington or Huntington's disease (HD) is an autosomal dominant
neurodegenerative disease characterised by both progressive motor and cognitive …

Sennoside A restrains TRAF6 level to modulate ferroptosis, inflammation and cognitive impairment in aging mice with Alzheimer's Disease

X Li, X Wang, B Huang, R Huang - International immunopharmacology, 2023 - Elsevier
Background Alzheimer's disease (AD) is a common neurodegenerative disease and a
momentous cause of dementia in the elderly. Sennoside A (SA) is an anthraquinone …

[HTML][HTML] The Encapsulation of Citicoline within Solid Lipid Nanoparticles Enhances Its Capability to Counteract the 6-Hydroxydopamine-Induced Cytotoxicity in Human …

A Margari, AG Monteduro, S Rizzato, L Capobianco… - Pharmaceutics, 2022 - mdpi.com
(1) Backgrond: Considering the positive effects of citicoline (CIT) in the management of
some neurodegenerative diseases, the aim of this work was to develop CIT-Loaded Solid …

[HTML][HTML] The dual role of heme oxygenase in regulating apoptosis in the nervous system of Drosophila melanogaster

TAL Abaquita, M Damulewicz, G Tylko… - Frontiers in Physiology, 2023 - frontiersin.org
Accumulating evidence from mammalian studies suggests the dual-faced character of heme
oxygenase (HO) in oxidative stress-dependent neurodegeneration. The present study aimed …

The role of ATP‐binding cassette transporter G1 (ABCG1) in Alzheimer's disease: A review of the mechanisms

MK Yazdi, MS Alavi… - Basic & Clinical …, 2024 - Wiley Online Library
The maintenance of cholesterol homeostasis is essential for central nervous system
function. Consequently, factors that affect cholesterol homeostasis are linked to neurological …