[HTML][HTML] Autophagy and its association with genetic mutations in parkinson disease

NS Erekat - Medical science monitor: international medical journal …, 2022 - ncbi.nlm.nih.gov
Parkinson disease is the second most common neurodegenerative disorder, affecting 0.1–
0.2% of the general population. It is a progressive debilitating disorder caused by …

[HTML][HTML] Mechanism of motoneuronal and pyramidal cell death in amyotrophic lateral sclerosis and its potential therapeutic modulation

B Nógrádi, D Nógrádi-Halmi, B Erdélyi-Furka… - Cell Death …, 2024 - nature.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder clinically
characterized by muscle atrophy and progressive paralysis. Loss of motoneurons and …

Farrerol attenuates glutamate-induced apoptosis in HT22 cells via the Nrf2/heme oxygenase-1 pathway

L Gao, T Wang, D Zhuoma, R Yuan… - Bioscience …, 2023 - academic.oup.com
Farrerol is a flavonoid found in plants with a wide range of pharmacological effects,
including protection and enhancement of nerve cell function, as well as antioxidant and …

The discovery of subunit-selective GluN1/GluN2B NMDAR antagonist via pharmacophere-based virtual screening

J Tang, J Jin, Z Huang, F An… - … Biology and Medicine, 2023 - journals.sagepub.com
The incidence and mortality rates of neurodegenerative diseases, such as Alzheimer's
disease and Parkinson's disease, are gradually increasing worldwide. Numerous studies …

Electromagnetic fields modulate inflammation and cell death in COVID-19 by acting on the immune system?

ME López-Martín, RA Sueiro-Benavides… - IEEE …, 2023 - ieeexplore.ieee.org
Programmed cell death constitutes a fundamental part of the immune response to viral
infection. This process forms part of the host defence mechanism and also enables …

Effect of doramectin on programmed cell death pathway in glioma cells

S Du, H Liang, L Zhou, C Chen, R Sun, J Zhang… - Clinical and …, 2023 - Springer
Purpose Doramectin (DRM) is a kind of avermectin drugs, and it has been shown that DRM
has anti-cancer effects. However, the molecular mechanism of DRM in programmed cell …

[HTML][HTML] Role of RB1 in neurodegenerative diseases: inhibition of post-mitotic neuronal apoptosis via Kmt5b

S Zhao, G Mo, Q Wang, J Xu, S Yu, Z Huang… - Cell Death …, 2024 - nature.com
During the development of the vertebrate nervous system, 50% of the nerve cells undergo
apoptosis shortly after formation. This process is important for sculpting tissue during …

[HTML][HTML] Butorphanol inhibits ferroptosis to attenuate PC12 cell injury by blocking JNK/p38 signaling

L Ji, Q She, P Zhou, Y Qin - Experimental and …, 2024 - spandidos-publications.com
Butorphanol is a synthetic selective opioid receptor antagonist that exhibits substantial
analgesic effects. The present study aimed to explore the effects of butorphanol on a …

[HTML][HTML] Bioactive substances in Hericium erinaceus and their biological properties: a review

Y Qiu, G Lin, W Liu, F Zhang, RJ Linhardt… - Food Science and …, 2024 - Elsevier
Hericium erinaceus is a nutritious edible and medicinal fungi, rich in a variety of functional
active ingredients, with various physiological functions such as antioxidation, anticancer …

[HTML][HTML] Caspase-dependent apoptosis in Riboflavin Transporter Deficiency iPSCs and derived motor neurons

C Marioli, M Muzzi, F Colasuonno, C Fiorucci… - Cell Death …, 2024 - nature.com
Abstract Riboflavin Transporter Deficiency (RTD) is a rare genetic, childhood-onset disease.
This pathology has a relevant neurological involvement, being characterized by motor …