[HTML][HTML] Advances in skeletal genomics research across tissues and cells
G Housman - Current Opinion in Genetics & Development, 2024 - Elsevier
Phenotypic variation within the skeleton has biological, behavioral, and biomedical
functional implications for individuals and species. Thus, it is critical to understand how …
functional implications for individuals and species. Thus, it is critical to understand how …
[HTML][HTML] The role of cytokine receptor-like factor 1 (CRLF1) in facet joint osteoarthritis pathogenesis
P Xue, H Jin, X Zhou, Z Cui, D Cui - Experimental Gerontology, 2024 - Elsevier
Background Facet joint osteoarthritis (FJOA) is a prevalent condition contributing to low back
pain, particularly in the elderly population. This study aimed to investigate the potential role …
pain, particularly in the elderly population. This study aimed to investigate the potential role …
[HTML][HTML] Transcriptomics and metabolomics: Challenges of studying obesity in osteoarthritis
Objective Obesity is a leading risk factor for both the incidence and progression of
osteoarthritis (OA). Omic technologies, including transcriptomics and metabolomics are …
osteoarthritis (OA). Omic technologies, including transcriptomics and metabolomics are …
CCL4/CCR5 regulates chondrocyte biology and OA progression
H Deng, P Xue, X Zhou, Y Wang, W Liu - Cytokine, 2024 - Elsevier
Background Osteoarthritis (OA) is a common musculoskeletal disorder characterized by
chondrocyte apoptosis and extracellular matrix degradation. This study aimed to investigate …
chondrocyte apoptosis and extracellular matrix degradation. This study aimed to investigate …
Transcriptome combined with single cell to explore hypoxia-related biomarkers in osteoarthritis
X Liu, G Li, R Liu, L Yang, L Li, A Goswami… - … of Chromatography B, 2024 - Elsevier
Osteoarthritis (OA) is a prevalent degenerative condition among the elderly on a global
scale. Research has demonstrated that hypoxia can promote chondrocyte apoptosis and …
scale. Research has demonstrated that hypoxia can promote chondrocyte apoptosis and …
Deep Learning-Based Multimodal Clustering Model for Endotyping and Post-Arthroplasty Response Classification using Knee Osteoarthritis Subject-Matched Multi …
Background Primary knee osteoarthritis (KOA) is a heterogeneous disease with clinical and
molecular contributors. Biofluids contain microRNAs and metabolites that can be measured …
molecular contributors. Biofluids contain microRNAs and metabolites that can be measured …