Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease–novel insights into cellular communication circuits

M Peiseler, R Schwabe, J Hampe, P Kubes… - Journal of …, 2022 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease and is
emerging as the leading cause of cirrhosis, liver transplantation and hepatocellular …

Current treatment of non‐alcoholic fatty liver disease

R Paternostro, M Trauner - Journal of internal medicine, 2022 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD) comprises a wide spectrum of pathologies
ranging from non‐alcoholic fatty liver (NAFL), characterized by simple steatosis without …

EASL Clinical Practice Guidelines on sclerosing cholangitis

O Chazouilleres, U Beuers, A Bergquist, TH Karlsen… - Journal of …, 2022 - Elsevier
Management of primary or secondary sclerosing cholangitis is challenging. These Clinical
Practice Guidelines have been developed to provide practical guidance on debated topics …

[HTML][HTML] TNF in the liver: targeting a central player in inflammation

G Tiegs, AK Horst - Seminars in immunopathology, 2022 - Springer
Tumour necrosis factor-α (TNF) is a multifunctional cytokine. First recognized as an
endogenous soluble factor that induces necrosis of solid tumours, TNF became increasingly …

Ferroptosis inhibitor liproxstatin-1 alleviates metabolic dysfunction-associated fatty liver disease in mice: potential involvement of PANoptosis

J Tong, X Lan, Z Zhang, Y Liu, D Sun, X Wang… - Acta Pharmacologica …, 2023 - nature.com
Ferroptosis is a new form of regulated cell death characterized by excessive iron
accumulation and uncontrollable lipid peroxidation. The role of ferroptosis in metabolic …

[HTML][HTML] Nuclear receptors linking metabolism, inflammation, and fibrosis in nonalcoholic fatty liver disease

T Puengel, H Liu, A Guillot, F Heymann… - International journal of …, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) and its progressive form nonalcoholic
steatohepatitis (NASH) comprise a spectrum of chronic liver diseases in the global …

[HTML][HTML] Advances in the diagnosis and treatment of non-alcoholic fatty liver disease

X Yin, X Guo, Z Liu, J Wang - International Journal of Molecular Sciences, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease that
affects approximately one-quarter of the global adult population, posing a significant threat …

[HTML][HTML] A new perspective on NAFLD: Focusing on the crosstalk between peroxisome proliferator-activated receptor alpha (PPARα) and farnesoid X receptor (FXR)

S Zhou, H You, S Qiu, D Yu, Y Bai, J He, H Cao… - Biomedicine & …, 2022 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is primarily caused by abnormal lipid metabolism
and the accumulation of triglycerides in the liver. NAFLD is also associated with hepatic …

Cholestasis: Exploring the triangular relationship of gut microbiota-bile acid-cholestasis and the potential probiotic strategies

L Yu, Y Liu, S Wang, Q Zhang, J Zhao, H Zhang… - Gut …, 2023 - Taylor & Francis
Cholestasis is a condition characterized by the abnormal production or excretion of bile, and
it can be induced by a variety of causes, the factors of which are extremely complex …

[HTML][HTML] Kaempferol attenuates nonalcoholic fatty liver disease in type 2 diabetic mice via the Sirt1/AMPK signaling pathway

N Li, L Yin, J Shang, M Liang, Z Liu, H Yang… - Biomedicine & …, 2023 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases with
limited treatment options. Moreover, its prevalence is doubled in type 2 diabetes mellitus …