[HTML][HTML] Models of intergenerational and transgenerational transmission of risk for psychopathology in mice

T Klengel, BG Dias, KJ Ressler - Neuropsychopharmacology, 2016 - nature.com
Trajectories toward risk or resilience in psychiatric disorders are influenced by acquired and
inherited factors. More recently, evidence from rodent studies suggest that acquired risk …

[HTML][HTML] Regulation of BDNF expression by cocaine

DM McCarthy, AN Brown, PG Bhide - The Yale journal of biology …, 2012 - ncbi.nlm.nih.gov
Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth
factors. It is expressed throughout the nervous system. A unique feature of the BDNF gene is …

Effects of prenatal cocaine/polydrug exposure on substance use by age 15

S Minnes, L Singer, MO Min, M Wu, A Lang… - Drug and alcohol …, 2014 - Elsevier
Objective Examined effects of prenatal cocaine exposure (PCE) on tobacco, alcohol,
marijuana and cocaine use by age 15. Methods Adolescent (n= 358; 183 PCE, 175 non …

Cocaine‐induced neurodevelopmental deficits and underlying mechanisms

MM Martin, DL Graham, DM McCarthy… - … Research Part C …, 2016 - Wiley Online Library
Exposure to drugs early in life has complex and long‐lasting implications for brain structure
and function. This review summarizes work to date on the immediate and long‐term effects …

Prenatal cocaine exposure increases anxiety, impairs cognitive function and increases dendritic spine density in adult rats: influence of sex

KY Salas-Ramirez, M Frankfurt, A Alexander, VN Luine… - Neuroscience, 2010 - Elsevier
Cocaine exposure during pregnancy can impact brain development and have long-term
behavioral consequences. The present study examined the lasting consequences of …

[HTML][HTML] Inhibitory effect of Berberis vulgaris aqueous extract on acquisition and reinstatement effects of morphine in conditioned place preferences (CPP) in mice

M Imenshahidi, R Qaredashi… - … journal of natural …, 2014 - ncbi.nlm.nih.gov
Background: It has been elucidated that Berberis vulgaris (barberry) can alleviate morphine
withdrawal syndrome. Also it has been reported that aqueous extract of barberry possibly …

Prenatal exposure to alcohol induces functional and structural plasticity in dopamine D1 receptor‐expressing neurons of the dorsomedial striatum

Y Cheng, X Wang, X Wei, X Xie, S Melo… - Alcoholism: Clinical …, 2018 - Wiley Online Library
Background Prenatal alcohol exposure (PAE) is a leading cause of hyperactivity in children.
Excitation of dopamine D1 receptor‐expressing medium spiny neurons (D1‐MSN s) of the …

Cocaine exposure in utero alters synaptic plasticity in the medial prefrontal cortex of postnatal rats

H Lu, B Lim, M Poo - Journal of Neuroscience, 2009 - Soc Neuroscience
Cocaine exposure during pregnancy causes abnormality in fetal brain development, leading
to cognitive dysfunction of the offspring, but the underlying cellular mechanism remains …

Maternal crack cocaine use in rats leads to depressive-and anxiety-like behavior, memory impairment, and increased seizure susceptibility in the offspring

ALD Pacheco, IS de Melo, FMA de Souza… - European …, 2021 - Elsevier
Crack users suffer the effects of cocaine present in the drug and the action of other active
compounds from its pyrolysis. An emergent fact is an increase in the number of pregnant …

[HTML][HTML] Efavirenz exposure, alone and in combination with known drugs of abuse, engenders addictive-like bio-behavioural changes in rats

M Möller, J Fourie, BH Harvey - Scientific reports, 2018 - nature.com
Efavirenz is abused in a cannabis-containing mixture known as Nyaope. The addictive-like
effects of efavirenz (5, 10 and 20 mg/kg) was explored using conditioned place preference …