Emerging PD-1/PD-L1 targeting immunotherapy in non-small cell lung cancer: Current status and future perspective in Japan, US, EU, and China

T Mizuno, Y Katsuya, J Sato, T Koyama… - Frontiers in …, 2022 - frontiersin.org
Non-small cell lung cancer (NSCLC), one of the deadliest types of cancers worldwide, has
been the target of immunotherapy due to its high immune antigenicity. With the addition of …

Serplulimab plus chemotherapy as first-line treatment for extensive-stage small-cell lung cancer: a cost-effectiveness analysis

Y Zhu, K Liu, Q Qin, H Zhu - Frontiers in immunology, 2023 - frontiersin.org
Introduction The ASTRUM-005 trial (NCT04063163) revealed that combination serplulimab
plus chemotherapy (etoposide and carboplatin EC) treatment was associated with survival …

Cost-Effectiveness of First-Line Immunotherapy for Advanced Non-Small Cell Lung Cancer with Different PD-L1 Expression Levels: A Comprehensive Overview

C Wu, W Li, H Tao, X Zhang, Y Xin, R Song… - Critical Reviews in …, 2023 - Elsevier
Background Immunotherapies can substantially improve treatment efficacy, despite their
high cost. A comprehensive overview of the cost-effectiveness analysis (CEA) of immune …

Cost-effectiveness analysis of tislelizumab, nivolumab and docetaxel as second-and third-line for advanced or metastatic non-small cell lung cancer in China

D Zhou, X Luo, Z Zhou, X Zeng, X Wan… - Frontiers in …, 2022 - frontiersin.org
Objective: Domestic PD-1inhibitor tislelizumab has emerged as a promising treatment for
Chinese patients with driver-negative advanced or metastatic non-small cell lung cancer …

Tislelizumab plus chemotherapy is more cost-effective than chemotherapy alone as first-line therapy for advanced non-squamous non-small cell lung cancer

X Liang, X Chen, H Li, Y Li - Frontiers in Public Health, 2023 - frontiersin.org
Background and objective Tislelizumab is a programmed cell death protein-1 (PD-1)
inhibitor. Tislelizumab plus chemotherapy as first-line option for advanced non-squamous …

Cost-effectiveness analysis of sugemalimab vs. chemotherapy as first-line treatment of metastatic nonsquamous non-small cell lung cancer

Z Zheng, H Zhu, L Fang, H Cai - Frontiers in Pharmacology, 2022 - frontiersin.org
Objective: Sugemalimab is approved in China as a first-line treatment in combination with
chemotherapy for metastatic nonsquamous non-small cell lung cancer (NSCLC). This study …

Cost‐effectiveness of first‐line versus second‐line use of domestic anti‐PD‐1 antibody sintilimab in Chinese patients with advanced or metastatic squamous non …

R Cheng, Z Zhou, Q Liu - Cancer Medicine, 2023 - Wiley Online Library
Background Programmed cell death protein‐1/programmed cell death ligand‐1 (PD‐1/L1)
inhibitor is a promising therapeutic option that can be used as either a first‐line or second …

Cost-effectiveness analysis of lenvatinib plus pembrolizumab compared with chemotherapy for patients with previously treated mismatch repair proficient advanced …

Z Zheng, L Yang, S Xu, H Zhu, H Cai - Frontiers in Pharmacology, 2022 - frontiersin.org
Aims: This study aimed to evaluate the cost-effectiveness of lenvatinib plus pembrolizumab
(LP) vs. chemotherapy for patients with previously treated mismatch repair proficient …

The cost-effectiveness of cemiplimab plus chemotherapy as the first-line treatment for advanced non-small cell lung cancer

T Lu, Y Huang, Z Cai, W Lin, X Chen… - Frontiers in …, 2023 - frontiersin.org
Background: The EMPOWER-LUNG 3 clinical trial has shown that cemiplimab plus
chemotherapy (CCT) significantly extended overall survival (OS) and progression-free …

A multicenter, real‐world study on effectiveness and safety of first‐line modified PD‐1 inhibitors with chemotherapy in advanced non‐small cell lung cancer (aNSCLC) …

T Li, C Chen, L Liu, J Qin, L Qiu, A Wang… - Cancer …, 2024 - Wiley Online Library
Objectives The use of immune checkpoint inhibitors, particularly PD‐1 inhibitors, has
revolutionized the treatment of advanced tumors and shown significant improvements in …