There are at least 21 families of enveloped viruses that infect mammals, and many contain
members of high concern for global human health. All enveloped viruses have a dedicated …

Innate immunity and the actions of type I and III interferons (IFNs) are essential for protection
from SARS-CoV-2 and COVID-19. Each is induced in response to infection and serves to …

Background Multiple viruses cocirculate and contribute to the burden of respiratory disease.
Virus-virus interactions can decrease susceptibility to infection and this interference can …

ABSTRACT A single-nucleotide polymorphism (SNP) rs12252-C of interferon-induced
transmembrane protein 3 (IFITM3), resulting in a truncated IFITM3 protein lacking 21 N …

Rabies, which caused by rabies virus (RABV), is a zoonotic and life-threatening disease with
100% mortality, and there is no effective treatment thus far due to the unclear pathogenesis …

Hepatitis C virus (HCV) alters gene expression epigenetically to rearrange the cellular
microenvironment in a beneficial way for its life cycle. The host epigenetic changes induced …

Background: Schizophrenia (SCZ) is a type of psychiatric disorder characterized by multiple
symptoms. Our aim is to decipher the relevant mechanisms of immune-related gene …

One of the ways to regulate the sensitivity of human cells to the influenza virus is to knock
out genes of the innate immune response. Promising targets for the knockout are genes of …

Zika virus is a re-merging flavivirus allied to serious mental health conditions in the fetuses.
There is currently no preventives or treatment available for Zika infection. In this work, we …

Objective To establish interferon-induced transmembrane protein 3 (Ifitm3) knockout mice
and to explore the effects of Ifitm3 on the proliferation and differentiation of adult neural stem …