Simple Summary The mitogen-activated protein kinase/extracellular signal-regulated kinase
(MAPK/ERK) signaling pathway is frequently activated in liver cancer, which is one of the …

Hepatocellular carcinoma (HCC) is the most frequent liver cancer with high lethality and low
five-year survival rates leading to a substantial worldwide burden for healthcare systems …

Background: Hepatocellular carcinoma (HCC) accounts for the majority of liver cancer, with
the incidence and mortality rates increasing every year. Despite the improvement of clinical …

The poor outcome of patients with non-surgically removable advanced hepatocellular
carcinoma (HCC), the most frequent type of primary liver cancer, is mainly due to the high …

Despite the recent introduction of new effective systemic agents, the survival of patients with
hepatocellular carcinoma (HCC) at advanced stages remains dismal. This underscores the …

Background: The continued success of oncological therapeutics is dependent on the
mitigation of treatment-related adverse events, particularly cardiovascular toxicities. As such …

Background Liver cancer is one of the common malignancies. The dysregulation of
metabolism is a driver of accelerated tumourigenesis. Metabolic changes are well …

Targeted therapies such as oral tyrosine kinase inhibitors (TKIs) are the main therapeutic
strategy effective for advanced hepatocellular carcinoma (HCC). Currently six tyrosine …

Abstract βII spectrin, the most common isoform of non-erythrocyte spectrin, is a cytoskeleton
protein present in all nucleated cells. Interestingly, βII spectrin is essential for the …

Core fucosylation of N-linked glycoproteins has been linked to the functions of glycoproteins
in physiological and pathological processes. However, quantitative characterization of core …