Immune response to SARS‐CoV‐2 and mechanisms of immunopathological changes in COVID‐19

AK Azkur, M Akdis, D Azkur, M Sokolowska… - Allergy, 2020 - Wiley Online Library
As a zoonotic disease that has already spread globally to several million human beings and
possibly to domestic and wild animals, eradication of coronavirus disease 2019 (COVID‐19) …

[HTML][HTML] COVID-19-associated acute respiratory distress syndrome: is a different approach to management warranted?

E Fan, JR Beitler, L Brochard, CS Calfee… - The Lancet …, 2020 - thelancet.com
The COVID-19 pandemic has seen a surge of patients with acute respiratory distress
syndrome (ARDS) in intensive care units across the globe. As experience of managing …

[HTML][HTML] Neutrophil extracellular traps mediate m6A modification and regulates sepsis-associated acute lung injury by activating ferroptosis in alveolar epithelial cells

H Zhang, J Liu, Y Zhou, M Qu, Y Wang… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Neutrophil extracellular traps (NETs) production is a major strategy employed by
polymorphonuclear neutrophils (PMNs) to fight against microbes. NETs have been …

Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study

G Cavalli, G De Luca, C Campochiaro… - The Lancet …, 2020 - thelancet.com
Background Mortality of patients with coronavirus disease 2019 (COVID-19), acute
respiratory distress syndrome (ARDS), and systemic inflammation is high. In areas of …

Effect of calcifediol treatment and best available therapy versus best available therapy on intensive care unit admission and mortality among patients hospitalized for …

ME Castillo, LME Costa, JMV Barrios, JFA Díaz… - The Journal of steroid …, 2020 - Elsevier
Objective The vitamin D endocrine system may have a variety of actions on cells and tissues
involved in COVID-19 progression especially by decreasing the Acute Respiratory Distress …

[HTML][HTML] Practical recommendations for critical care and anesthesiology teams caring for novel coronavirus (2019-nCoV) patients

RS Wax, MD Christian - Canadian Journal of Anesthesia/Journal canadien …, 2020 - Springer
A global health emergency has been declared by the World Health Organization as the
2019-nCoV outbreak spreads across the world, with confirmed patients in Canada. Patients …

[PDF][PDF] COVID‐19 acute respiratory distress syndrome (ARDS): clinical features and differences from typical pre‐COVID‐19 ARDS

PG Gibson, L Qin, SH Puah - The Medical Journal of Australia, 2020 - mja.com.au
“This disease is still too strange to us, and there are too many doubts”, says Dr Ling Qin
(LQ), after reviewing more than 400 patients with coronavirus disease 2019 (COVID-19) …

The Japanese clinical practice guidelines for management of sepsis and septic shock 2020 (J-SSCG 2020)

M Egi, H Ogura, T Yatabe, K Atagi, S Inoue, T Iba… - Journal of intensive …, 2021 - Springer
Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …

Mesenchymal stromal/stem cell (MSC)-derived exosomes in clinical trials

A Lotfy, NM AboQuella, H Wang - Stem Cell Research & Therapy, 2023 - Springer
Mesenchymal stromal/stem cells (MSCs) are widely utilized in cell therapy because of their
robust immunomodulatory and regenerative properties. Their paracrine activity is one of the …

In-hospital use of statins is associated with a reduced risk of mortality among individuals with COVID-19

XJ Zhang, JJ Qin, X Cheng, L Shen, YC Zhao, Y Yuan… - Cell metabolism, 2020 - cell.com
Statins are lipid-lowering therapeutics with favorable anti-inflammatory profiles and have
been proposed as an adjunct therapy for COVID-19. However, statins may increase the risk …