The H19 locus: Role of an imprinted non‐coding RNA in growth and development
A Gabory, H Jammes, L Dandolo - Bioessays, 2010 - Wiley Online Library
The H19 gene produces a non‐coding RNA, which is abundantly expressed during
embryonic development and down‐regulated after birth. Although this gene was discovered …
embryonic development and down‐regulated after birth. Although this gene was discovered …
Epigenetic events in mammalian germ-cell development: reprogramming and beyond
H Sasaki, Y Matsui - Nature Reviews Genetics, 2008 - nature.com
The epigenetic profile of germ cells, which is defined by modifications of DNA and
chromatin, changes dynamically during their development. Many of the changes are …
chromatin, changes dynamically during their development. Many of the changes are …
Dnmt3L and the establishment of maternal genomic imprints
Complementary sets of genes are epigenetically silenced in male and female gametes in a
process termed genomic imprinting. The Dnmt3L gene is expressed during gametogenesis …
process termed genomic imprinting. The Dnmt3L gene is expressed during gametogenesis …
Intercellular communication in the mammalian ovary: oocytes carry the conversation
The production of functional female gametes is essential for the propagation of all vertebrate
species. The growth of oocytes within ovarian follicles and their development to mature eggs …
species. The growth of oocytes within ovarian follicles and their development to mature eggs …
[PDF][PDF] Primordial germ cells in the mouse
A McLaren - Developmental biology, 2003 - core.ac.uk
Germ cells may be defined as those cells, all of whose surviving descendants will become
sperm or eggs. In all sexually reproducing animals and plants, these cells play a uniquely …
sperm or eggs. In all sexually reproducing animals and plants, these cells play a uniquely …
[HTML][HTML] Genomic imprinting disrupted by a maternal effect mutation in the Dnmt1 gene
Maintenance of genomic methylation patterns in mammalian somatic cells depends on DNA
methyltransferase-1 (Dnmt1). Mouse oocytes and preimplantation embryos lack Dnmt1 but …
methyltransferase-1 (Dnmt1). Mouse oocytes and preimplantation embryos lack Dnmt1 but …
Human embryos from overweight and obese women display phenotypic and metabolic abnormalities
C Leary, HJ Leese, RG Sturmey - Human reproduction, 2015 - academic.oup.com
STUDY QUESTION Is the developmental timing and metabolic regulation disrupted in
embryos from overweight or obese women? SUMMARY ANSWER Oocytes from overweight …
embryos from overweight or obese women? SUMMARY ANSWER Oocytes from overweight …
Genomic imprinting at the mammalian Dlk1-Dio3 domain
Genomic imprinting causes genes to be expressed or repressed depending on their
parental origin. The majority of imprinted genes identified to date map in clusters and much …
parental origin. The majority of imprinted genes identified to date map in clusters and much …
Nuclear cloning and epigenetic reprogramming of the genome
WM Rideout III, K Eggan, R Jaenisch - Science, 2001 - science.org
Cloning of mammals by nuclear transfer (NT) results in gestational or neonatal failure with at
most a few percent of manipulated embryos resulting in live births. Many of those that …
most a few percent of manipulated embryos resulting in live births. Many of those that …
Birth of parthenogenetic mice that can develop to adulthood
T Kono, Y Obata, Q Wu, K Niwa, Y Ono, Y Yamamoto… - Nature, 2004 - nature.com
Only mammals have relinquished parthenogenesis, a means of producing descendants
solely from maternal germ cells. Mouse parthenogenetic embryos die by day 10 of …
solely from maternal germ cells. Mouse parthenogenetic embryos die by day 10 of …