CRISPR/Cas9 and next generation sequencing in the personalized treatment of Cancer

SC Selvakumar, KA Preethi, K Ross, D Tusubira… - Molecular Cancer, 2022 - Springer
Background Cancer is caused by a combination of genetic and epigenetic abnormalities.
Current cancer therapies are limited due to the complexity of their mechanism, underlining …

Liquid biopsies, novel approaches and future directions

A Armakolas, M Kotsari, J Koskinas - Cancers, 2023 - mdpi.com
Simple Summary The gold standard for detecting cancer and profiling tumors is tissue
biopsies. Despite this, tissue biopsies have been associated with many limitations leading to …

Potential clinical utility of liquid biopsy in early-stage non-small cell lung cancer

H Shen, Y Jin, H Zhao, M Wu, K Zhang, Z Wei, X Wang… - BMC medicine, 2022 - Springer
Background Liquid biopsy has been widely researched for early diagnosis, prognostication
and disease monitoring in lung cancer, but there is a need to investigate its clinical utility for …

[HTML][HTML] Liquid biopsy-based decision support algorithms for diagnosis and subtyping of lung cancer

E Visser, SAAM Genet, RPPA de Kock… - Lung Cancer, 2023 - Elsevier
Objectives Pathologic subtyping of tissue biopsies is the gold standard for the diagnosis of
lung cancer (LC), which could be complicated in cases of eg inconclusive tissue biopsies or …

Expert opinion on NSCLC small specimen biomarker testing—Part 2: Analysis, reporting, and quality assessment

F Penault-Llorca, KM Kerr, P Garrido, E Thunnissen… - Virchows Archiv, 2022 - Springer
The diagnostic work-up for non-small cell lung cancer (NSCLC) requires biomarker testing
to guide therapy choices. This article is the second of a two-part series. In Part 1, we …

Liquid biopsies in lung cancer

M Kemper, C Krekeler, K Menck, G Lenz, G Evers… - Cancers, 2023 - mdpi.com
Simple Summary Liquid biopsy has recently been introduced as a novel method in cancer
diagnostics. It is less invasive for patients than conventional tissue biopsies, as the assay …

Accelerating the development and validation of liquid biopsy for early cancer screening and treatment tailoring

D Horgan, T Čufer, F Gatto, I Lugowska, D Verbanac… - Healthcare, 2022 - mdpi.com
Liquid biopsy (LB) is a minimally invasive method which aims to detect circulating tumor-
derived components in body fluids. It provides an alternative to current cancer screening …

Liquid biopsy in lung cancer: biomarkers for the management of recurrence and metastasis

VGP Souza, A Forder, LJ Brockley… - International Journal of …, 2023 - mdpi.com
Liquid biopsies have emerged as a promising tool for the detection of metastases as well as
local and regional recurrence in lung cancer. Liquid biopsy tests involve analyzing a …

Liquid biopsy in early-stage lung cancer: Current and Future Clinical Applications

O Vandekerckhove, K Cuppens, K Pat, B Du Pont… - Cancers, 2023 - mdpi.com
Simple Summary Early-stage disease non-small cell lung cancer has better outcomes than
advanced disease, but 5-year survival rates can drop to approximately 50% in cases of …

[HTML][HTML] Current and future applications of liquid biopsy in non-small-cell lung cancer—a narrative review

B Tomasik, M Skrzypski, M Bieńkowski… - Translational Lung …, 2023 - ncbi.nlm.nih.gov
Current and future applications of liquid biopsy in non-small-cell lung cancer—a narrative
review - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …