The role of exosomes in the pathogenesis of pancreatic ductal adenocarcinoma
SM Robinson, L Fan, SA White, RM Charnley… - The International Journal …, 2016 - Elsevier
Exosomes are small membrane bound vesicles secreted by cancer cells that have a cytosol
rich in proteins and nucleic acids which are capable of modulating the phenotype of …
rich in proteins and nucleic acids which are capable of modulating the phenotype of …
Precursors of pancreatic cancer
P Fric, J Škrha, A Šedo, P Bušek, M Laclav… - European Journal of …, 2017 - journals.lww.com
Pancreatic cancer (PC) behaves very differently in comparison with other malignancies. Its
incidence has been increasing continuously; mortality has not decreased, the diagnosis is …
incidence has been increasing continuously; mortality has not decreased, the diagnosis is …
Increased risk of second primary cancers following diagnosis of malignant intraductal papillary mucinous neoplasms of the pancreas: a population-based study
X Huang, B Zhang, J Zhao, C Sun, K Kong… - Frontiers in …, 2019 - frontiersin.org
Introduction: Several studies have reported that intraductal papillary mucinous neoplasms
(IPMNs) of the pancreas are associated with extra-pancreatic malignancies. However, there …
(IPMNs) of the pancreas are associated with extra-pancreatic malignancies. However, there …
[HTML][HTML] Functioning and nonfunctioning pNENs
K Daskalakis - Current Opinion in Endocrine and Metabolic Research, 2021 - Elsevier
Pancreatic neuroendocrine neoplasms (pNENs) are relatively rare tumors that have been
increasingly recognized in recent years. They are highly heterogeneous and exhibit a …
increasingly recognized in recent years. They are highly heterogeneous and exhibit a …
Mutational spectrum of intraepithelial neoplasia in pancreatic heterotopia
Heterotopic pancreatic parenchyma recapitulates the normal pancreas in extrapancreatic
locations and, on rare occasions, can even give rise to pancreatic adenocarcinoma. The …
locations and, on rare occasions, can even give rise to pancreatic adenocarcinoma. The …
The Effect of Intratumor Heterogeneity in Pancreatic Ductal Adenocarcinoma Progression and Treatment
O Saleh, H Shihadeh, A Yousef, H Erekat, F Abdallh… - Pancreas, 2024 - journals.lww.com
Materials and Methods The search process used PubMed, Cochrane Library, and Scopus
databases to identify the relevant and related articles. Articles had to be published in English …
databases to identify the relevant and related articles. Articles had to be published in English …
[HTML][HTML] Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer
TA Mace, R Shakya, O Elnaggar, K Wilson, HM Komar… - Oncotarget, 2015 - ncbi.nlm.nih.gov
The Jak/STAT pathway is activated in human pancreatic ductal adenocarcinoma (PDAC)
and cooperates with mutant Kras to drive initiation and progression of PDAC in murine …
and cooperates with mutant Kras to drive initiation and progression of PDAC in murine …
A screen for extracellular signal-regulated kinase-primed glycogen synthase kinase 3 substrates identifies the p53 inhibitor iASPP
The Kaposi's sarcoma-associated herpesvirus (KSHV) LANA protein is essential for the
replication and maintenance of virus genomes in latently KSHV-infected cells. LANA also …
replication and maintenance of virus genomes in latently KSHV-infected cells. LANA also …
Loss of BAP1 expression is very rare in pancreatic ductal adenocarcinoma
M Tayao, J Andrici, M Farzin, A Clarkson, L Sioson… - PloS one, 2016 - journals.plos.org
Background Pancreatic cancer is both common and highly lethal and therefore new
biomarkers or potential targets for treatment are needed. Loss of BRCA associated protein-1 …
biomarkers or potential targets for treatment are needed. Loss of BRCA associated protein-1 …
Genetics of pancreatic neoplasms and role of screening
VS Katabathina, OY Rikhtehgar… - Magnetic …, 2018 - mri.theclinics.com
The broad spectrum of pancreatic neoplasms may be classified based on the direction of
cellular differentiation into exocrine and endocrine tumors. Pancreatic ductal …
cellular differentiation into exocrine and endocrine tumors. Pancreatic ductal …