Background The Penumbra system is effective for recanalization of the primary arterial
occlusion (PAO) in acute stroke. However, clinical outcomes are not as promising. The …

Objective Tandem cervical carotid and intracranial occlusions are a well-known cause of
complicated endovascular thrombectomy (EVT) in acute ischemic stroke. We aimed to …

Introduction Porcine thrombi are employed routinely in preclinical models of ischemic stroke.
In this study, we examined the differential lytic susceptibility of porcine and human whole …

ABSTRACT BACKGROUND AND PURPOSE To establish outcome rates for patients
receiving intravenous thrombolysis based on vascular occlusion site. METHODS This is a …

Background Recent trials established the efficacy of mechanical stent-retriever
thrombectomy for treatment of stroke patients with large vessel occlusion (LVO) in the …

BACKGROUND AND PURPOSE: Occlusion of major cerebral arteries is the primary source
of tissue damage in ischemic stroke and the target of thrombolytic therapy. We hypothesized …

OBJECTIVE: Intracranial large-vessel ischemia is associated with poor clinical outcome and
increased mortality. Early reperfusion of ischemic tissue remains the goal of treatment of …

Introduction Despite intravenous thrombolysis (IVT) and endovascular treatment (EVT) have
been demonstrated effective in acute ischemic stroke (AIS) due to large vessel occlusions …

PURPOSE: Time from stroke onset to treatment (OTT) is potentially an important factor
affecting subsequent outcome in patients treated with t-PA. The aim of the study was to …