[HTML][HTML] The role of extracellular matrix components in inflammatory bowel diseases

A Derkacz, P Olczyk, K Olczyk… - Journal of Clinical …, 2021 - mdpi.com
The remodeling of extracellular matrix (ECM) within the intestine tissues, which
simultaneously involves an increased degradation of ECM components and excessive …

[HTML][HTML] Activation of resolution pathways to prevent and fight chronic inflammation: lessons from asthma and inflammatory bowel disease

C Barnig, T Bezema, PC Calder, A Charloux… - Frontiers in …, 2019 - frontiersin.org
Formerly considered as a passive process, the resolution of acute inflammation is now
recognized as an active host response, with a cascade of coordinated cellular and …

Advances in our understanding of gout as an auto-inflammatory disease

S Bodofsky, TR Merriman, TJ Thomas… - Seminars in Arthritis and …, 2020 - Elsevier
Gout, the most common inflammatory arthritis, is the result of hyperuricemia and
inflammation induced by monosodium urate (MSU) crystal deposition. However, most …

Correlation between interleukin gene polymorphisms and current prevalence and mortality rates due to novel coronavirus disease 2019 (COVID‐2019) in 23 countries

L Karcioglu Batur, N Hekim - Journal of Medical Virology, 2021 - Wiley Online Library
Background The novel coronavirus disease 2019 (COVID‐19) infection may rely on a
potential genetic background for the variations in the inflammatory response. We aimed to …

[HTML][HTML] Anti-inflammatory effects of sacral nerve stimulation: a novel spinal afferent and vagal efferent pathway

L Tu, P Gharibani, N Zhang, J Yin… - American Journal of …, 2020 - journals.physiology.org
Sacral nerve stimulation (SNS) was reported to improve 2, 4, 6-trinitrobenzenesulfonic acid
(TNBS)-induced colitis in rats. The aim of this study was to investigate whether the SNS anti …

Differential intestinal mucosa transcriptomic biomarkers for Crohn's disease and ulcerative colitis

M Dobre, E Milanesi, TE Mănuc… - Journal of …, 2018 - Wiley Online Library
Genetic research has shaped the inflammatory bowel disease (IBD) landscape identifying
nearly two hundred risk loci. Nonetheless, the identified variants rendered only a partial …

[HTML][HTML] Gene signatures of early response to anti-TNF drugs in pediatric inflammatory bowel disease

S Salvador-Martín, I Raposo-Gutiérrez… - International journal of …, 2020 - mdpi.com
Around a 20–30% of inflammatory bowel disease (IBD) patients are diagnosed before they
are 18 years old. Anti-TNF drugs can induce and maintain remission in IBD, however, up to …

Sacral nerve stimulation ameliorates colonic barrier functions in a rodent model of colitis

L Tu, P Gharibani, J Yin… - Neurogastroenterology & …, 2020 - Wiley Online Library
Background The mucosal barrier damage is recognized as one of the key factors in the
pathogenesis of colitis. While sacral nerve stimulation (SNS) was reported to have …

Genetic predictors of long-term response and trough levels of infliximab in crohn's disease

S Salvador-Martín, B López-Cauce, O Nuñez… - Pharmacological …, 2019 - Elsevier
Introduction Several factors, such as trough serum anti-TNF levels, have been associated
with response to therapy in Crohn's disease. However, this association is observed after …

Association of inflammatory cytokine gene polymorphisms with inflammatory bowel disease in a Moroccan cohort

N Senhaji, A Serrano, W Badre, N Serbati… - Genes & …, 2016 - nature.com
The purpose of this study was to investigate whether common variants in inflammatory and
immune response genes influence inflammatory bowel disease (IBD) risk among Moroccan …