Abstract In 1956, Riker Laboratories, Inc.,(now 3 M Drug Delivery Systems) introduced the
first pressurized metered dose inhaler (MDI). In many respects, the introduction of the MDI …

In the 50 years following the introduction of the first dry powder inhaler to the market, several
developments have occurred. Multiple-unit dose and multi-dose devices have been …

The advent of nanotechnology has reignited interest in the lungs as a major route of drug
delivery for both systemic and local treatments. The large surface area of the lungs and the …

The efficacy of pharmaceutical aerosols relates to its deposition in the clinically relevant
regions of the lungs, which can be assessed by in vivo lung deposition studies. Dry powder …

Pulmonary drug delivery is the focus of much research and development because of its
great potential to produce maximum therapeutic benefit. Among the available options the dry …

Abstract A Dry Powder Inhaler (DPI) is a technique as well as a device used to inhale
formulation which is in the form of dry powder, and is inhaled through the nose or mouth. It …

Background Asthma and chronic obstructive pulmonary disease (COPD) are common
chronic inflammatory respiratory diseases, which impose a substantial burden on healthcare …

Objective: Correct inhaler technique is central to effective delivery of asthma therapy. The
study aim was to identify factors associated with serious inhaler technique errors and their …

Ideally, inhaled therapy is driven by the needs of specific disease management. Lung
biology interfaces with inhaler performance to allow optimal delivery of therapeutic agent for …

Abstract Background: European and United States Pharmacopoeia compendial procedures
for assessing the in vitro emitted dose and aerodynamic size distribution of a dry powder …