A comprehensive review on time-tested anticancer drug doxorubicin

S Sritharan, N Sivalingam - Life sciences, 2021 - Elsevier
Doxorubicin or Adriamycin, is one of the most widely used chemotherapeutic drug for
treating a myriad of cancers. It induces cell death through multiple intracellular targets …

Cancer in sub-Saharan Africa: a lancet oncology commission

W Ngwa, BW Addai, I Adewole, V Ainsworth… - The Lancet …, 2022 - thelancet.com
Summary In sub-Saharan Africa (SSA), urgent action is needed to curb a growing crisis in
cancer incidence and mortality. Without rapid interventions, data estimates show a major …

Doxorubicin-based hybrid compounds as potential anticancer agents: a review

S Peter, S Alven, RB Maseko, BA Aderibigbe - Molecules, 2022 - mdpi.com
The scarcity of novel and effective therapeutics for the treatment of cancer is a pressing and
alarming issue that needs to be prioritized. The number of cancer cases and deaths are …

Global burden of head and neck cancer: economic consequences, health, and the role of surgery

RH Patterson, VG Fischman… - … –Head and Neck …, 2020 - journals.sagepub.com
Objective We aimed to describe the mortality burden and macroeconomic effects of head
and neck cancer as well as delineate the role of surgical workforce in improving head and …

Global demand for cancer surgery and an estimate of the optimal surgical and anaesthesia workforce between 2018 and 2040: a population-based modelling study

SK Perera, S Jacob, BE Wilson, J Ferlay, F Bray… - The Lancet …, 2021 - thelancet.com
Background The growing demand for cancer surgery has placed a global strain on health
systems. In-depth analyses of the global demand for cancer surgery and optimal workforce …

Nanomaterials as an advanced nano-tool for the doxorubicin delivery/Co-Delivery—A comprehensive review

R Arshad, MS Arshad, A Rahdar, D Hassan… - Journal of Drug Delivery …, 2023 - Elsevier
Cancer is the deadliest multifactorial disease, constituting variations at the molecular and
histological level. Cancer is being treated on advanced step via utilization of the multiple …

Prevention and treatment of chemotherapy-induced alopecia: what is available and what is coming?

TC Wikramanayake, NI Haberland, A Akhundlu… - Current …, 2023 - mdpi.com
Millions of new cancer patients receive chemotherapy each year. In addition to killing cancer
cells, chemotherapy is likely to damage rapidly proliferating healthy cells, including the hair …

Glycopolymer decorated multiwalled carbon nanotubes for dual targeted breast cancer therapy

PSO Ozgen, S Atasoy, BZ Kurt, Z Durmus… - Journal of Materials …, 2020 - pubs.rsc.org
Carbon-based nanomaterials (CNMs) have attracted great attention in biomedical
applications such as cancer imaging and therapy. CNMs, which are currently used in a wide …

[PDF][PDF] Pharmacological boosting of cGAS activation sensitizes chemotherapy by enhancing antitumor immunity

H Liu, H Su, F Wang, Y Dang, Y Ren, S Yin, H Lu… - Cell Reports, 2023 - cell.com
Enhancing chemosensitivity is one of the largest unmet medical needs in cancer therapy.
Cyclic GMP-AMP synthase (cGAS) connects genome instability caused by platinum-based …

Breast cancer screening in low and middle-income countries

LA Newman - Best Practice & Research Clinical Obstetrics & …, 2022 - Elsevier
Breast cancer incidence rates are rising in low and middle-income countries (LMIC), and
these populations have reduced access to advanced multidisciplinary treatment. Screening …