Angiogenic therapy, which involves the use of an exogenous stimulus to promote blood
vessel growth, is an attractive approach for the treatment of ischemic diseases. It has been …

There is evidence that glucocorticoids reduce infarct size but their use in myocardial
infarction remains controversial because of their potential adverse effects on healing of the …

Models for the study of arrhythmias in myocardial ischaemia and infarction: the use of the rat -
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Cardiac pacemaking offers a unique opportunity for direct gene transfer into the heart. An
experimental system was developed to assay the effects of transferring the human beta2 …

The diuretic and natriuretic effects of r‐α‐ANP (99–126) were investigated in rats with
chronic ischaemic heart failure (IHF) produced by left coronary artery ligation. The plasma …

Background Accumulating evidence suggests glucagon-like peptide-1 (GLP-1) exerts
cardioprotective effects in animal models of myocardial infarction (MI). We hypothesized that …

For determination of the effects of myocardial infarction on the recovery potential of muscle
mass in the surviving tissue, ligation of the left coronary artery was performed in 3-month-old …

Background: Types I and III collagen have different physical properties, and an increase of
type I/III ratio can have a deleterious impact on myocardial compliance and left and right …

We previously reported that hypoxia followed by reoxygenation (hypoxia/reoxygenation)
rapidly activated intracellular signaling such as mitogen-activated protein kinases (MAPKs) …

To elucidate the mechanism (s) of myocardial reperfusion injury, we investigated the roles of
cell adhesion molecules on both leukocytes and vascular endothelial cells in the reperfused …