Role of endothelin in the maintenance of blood pressure in conscious rats with chronic heart failure. Acute effects of the endothelin receptor antagonist Ro 47-0203 …

JR Teerlink, BM Löffler, P Hess, JP Maire, M Clozel… - Circulation, 1994 - Am Heart Assoc
BACKGROUND Endothelin (ET) is a potent vasoconstrictor, and its concentration is
increased in patients with heart failure. The purpose of this study was to investigate the role …

Immunohistochemical study of fibronectin in experimental myocardial infarction.

W Casscells, H Kimura, JA Sanchez, ZX Yu… - The American journal …, 1990 - ncbi.nlm.nih.gov
Light microscopic immunohistochemical studies were performed to evaluate the distribution
of fibronectin in paraffin sections of p-formaldehyde-fixed normal rat hearts and the hearts of …

Antioxidants attenuate myocyte apoptosis in the remote non-infarcted myocardium following large myocardial infarction

HJ Oskarsson, L Coppey, RM Weiss… - Cardiovascular …, 2000 - academic.oup.com
Objective: Increased oxidative stress and myocyte apoptosis co-exist in the remote non-
infarcted myocardium (RM) following a large myocardial infarction. We proposed that these …

Long-term preservation of ischemic myocardium after experimental coronary artery occlusion

D Maclean, MC Fishbein, E Braunwald… - The Journal of …, 1978 - Am Soc Clin Investig
The results of experiments with indirect methods have suggested that various interventions
reduce infarct size after coronary artery occlusion. To determine and quantify directly both …

Antibody to platelet/endothelial cell adhesion molecule-1 reduces myocardial infarct size in a rat model of ischemia-reperfusion injury

RJ Gumina, JE Schultz, Z Yao, D Kenny, DC Warltier… - Circulation, 1996 - Am Heart Assoc
Background Antibodies to selected neutrophil or endothelial cell adhesion molecules
decrease myocardial infarct size in vivo. Platelet/endothelial cell adhesion molecule-1 …

New insights into the pathological role of TNF-α in early cardiac dysfunction and subsequent heart failure after infarction in rats

C Berthonneche, T Sulpice, F Boucher… - American Journal …, 2004 - journals.physiology.org
A marked increase in plasma TNF-α has been described in patients with chronic heart
failure (CHF). Nevertheless, little is known about the direct role of this cytokine early after …

Heart fatty acid binding protein as a marker for postmortem detection of early myocardial damage

X Meng, M Ming, E Wang - Forensic science international, 2006 - Elsevier
Depletion of heart fatty acid binding protein (H-FABP) from cardiomyocytes with varying post-
ischemia intervals was studied in acute myocardial infarction (AMI) model of rat, and 22 …

Effects of afterload-reducing drugs on pathogenesis of antioxidant changes and congestive heart failure in rats

N Khaper, PK Singal - Journal of the American College of Cardiology, 1997 - jacc.org
Objectives. The present study sought to evaluate the effects of the afterload-reducing drugs
captopril and prazosin on changes in antioxidants as well as oxidative stress in relation to …

Increased cardiac expression of endothelin-1 mRNA in ischemic heart failure in rats

T Tønnessen, G Christensen, E Øie, E Holt… - Cardiovascular …, 1997 - academic.oup.com
Objectives: Plasma endothelin (ET) concentrations are increased in heart failure. The aims
of the present study were to investigate to what extent cardiac ET mRNA expression is …

Temporal relation between neutrophil accumulation and myocardial reperfusion injury

EF Smith 3rd, JW Egan, PJ Bugelski… - American Journal …, 1988 - journals.physiology.org
Infiltration of polymorphonuclear leukocytes (PMN) is associated with the progression of
myocardial infarction and reperfusion injury. However, little is known about the time course …