[HTML][HTML] Pharmacological basis and new insights of taxifolin: A comprehensive review

A Das, R Baidya, T Chakraborty, AK Samanta… - Biomedicine & …, 2021 - Elsevier
The pharmacological characteristics of phytochemicals have prompted a lot of interest in
their application in disease management. Due to the high incidence of cancer related …

Mediterranean diet nutrients to turn the tide against insulin resistance and related diseases

M Mirabelli, E Chiefari, B Arcidiacono, DM Corigliano… - Nutrients, 2020 - mdpi.com
Insulin resistance (IR), defined as an attenuated biological response to circulating insulin, is
a fundamental defect in obesity and type 2 diabetes (T2D), and is also linked to a wide …

Cardio-metabolic effects of high-fat diets and their underlying mechanisms—A narrative review

JA Wali, N Jarzebska, D Raubenheimer, SJ Simpson… - Nutrients, 2020 - mdpi.com
The majority of the epidemiological evidence over the past few decades has linked high
intake of fats, especially saturated fats, to increased risk of diabetes and cardiovascular …

Preventive role of diet interventions and dietary factors in type 2 diabetes mellitus: an umbrella review

PL Toi, T Anothaisintawee, U Chaikledkaew… - Nutrients, 2020 - mdpi.com
Background: Although the body of evidence indicates clear benefits of dietary modifications
for prevention of type-2 diabetes mellitus (T2DM), it may be difficult for healthcare providers …

Dietary and policy priorities to reduce the global crises of obesity and diabetes

D Mozaffarian - Nature Food, 2020 - nature.com
The world faces a global nutrition crisis, most clearly evidenced by the twin pandemics of
obesity and type 2 diabetes (T2DM). Yet, substantial confusion and controversy exist about …

Dietary flavonoids for immunoregulation and cancer: Food design for targeting disease

JH Ahn-Jarvis, A Parihar, AI Doseff - Antioxidants, 2019 - mdpi.com
Flavonoids, one of the most abundant phytochemicals in a diet rich in fruits and vegetables,
have been recognized as possessing anti-proliferative, antioxidant, anti-inflammatory, and …

Plants secondary metabolites as blood glucose-lowering molecules

MB Shehadeh, GARY Suaifan, AM Abu-Odeh - Molecules, 2021 - mdpi.com
Recently, significant advances in modern medicine and therapeutic agents have been
achieved. However, the search for effective antidiabetic drugs is continuous and …

Comparative study of dietary flavonoids with different structures as α-glucosidase inhibitors and insulin sensitizers

Y Jia, Y Ma, G Cheng, Y Zhang… - Journal of Agricultural and …, 2019 - ACS Publications
This work was designed to comparatively investigate 27 dietary flavonoids that act as α-
glucosidase inhibitors and insulin sensitizers. On the basis of the results of an in vitro …

Bioactivity of natural biflavonoids in metabolism-related disease and cancer therapies

JC Menezes, MF Diederich - Pharmacological Research, 2021 - Elsevier
Natural biflavonoids, such as amentoflavone, bilobetin, ginkgetin, isoginkgetin,
taiwaniaflavone, morelloflavone, delicaflavone, hinokiflavone, and other derivatives (~ 40 …

[HTML][HTML] Flavonoids as alpha-glucosidase inhibitors: Mechanistic approaches merged with enzyme kinetics and molecular modelling

D Şöhretoğlu, S Sari - Phytochemistry Reviews, 2020 - Springer
Diabetes mellitus is a major, global public health problem. α-Glucosidase inhibitors are one
of the most widely used classes of oral antidiabetics. In addition to other pharmaceutical …