[HTML][HTML] Enhancing immunotherapy response in melanoma: myeloid-derived suppressor cells as a therapeutic target

FGO Kurt, S Lasser, I Arkhypov, J Utikal… - The Journal of …, 2023 - Am Soc Clin Investig
Despite the remarkable success of immune checkpoint inhibitors (ICIs) in melanoma
treatment, resistance to them remains a substantial clinical challenge. Myeloid-derived …

Tumor-infiltrating lymphocyte therapy in melanoma: facts to the future

A Betof Warner, PG Corrie, O Hamid - Clinical Cancer Research, 2023 - AACR
Adoptive cell therapy with tumor-infiltrating lymphocytes (TIL) is gaining momentum and
demonstrating durable responses in patients with advanced melanoma. Although …

Encapsulation of platinum prodrugs into PC7A polymeric nanoparticles combined with immune checkpoint inhibitors for therapeutically enhanced multimodal …

X Gao, G Lei, B Wang, Z Deng, J Karges… - Advanced …, 2023 - Wiley Online Library
Tumor immunotherapy has emerged as one of the most promising therapeutic methods to
treat cancer. Despite its clinical application, the immunosuppressive tumor …

Dissolvable Self‐Locking Microneedle Patches Integrated with Immunomodulators for Cancer Immunotherapy

SH Joo, J Kim, J Hong, S Fakhraei Lahiji… - Advanced …, 2023 - Wiley Online Library
Advancements in micro‐resolution 3D printers have significantly facilitated the development
of highly complex mass‐producible drug delivery platforms. Conventionally, due to the …

Exosome camouflaged coordination-assembled Iridium (III) photosensitizers for apoptosis-autophagy-ferroptosis induced combination therapy against melanoma

T Feng, Z Tang, J Karges, J Shen, C Jin, Y Chen, Y Pan… - Biomaterials, 2023 - Elsevier
Melanoma represents the most fatal form of skin cancer due to its resistance mechanisms
and high capacity for the development of metastases. Among other medicinal techniques …

[HTML][HTML] Phenotype switching and the melanoma microenvironment; impact on immunotherapy and drug resistance

SM Hossain, MR Eccles - International journal of molecular sciences, 2023 - mdpi.com
Melanoma, a highly heterogeneous tumor, is comprised of a functionally diverse spectrum of
cell phenotypes and subpopulations, including stromal cells in the tumor microenvironment …

[HTML][HTML] The role of mitochondria in the resistance of melanoma to PD-1 inhibitors

F Du, L Yang, J Liu, J Wang, L Fan… - Journal of Translational …, 2023 - Springer
Malignant melanoma is one of the most common tumours and has the highest mortality rate
of all types of skin cancers worldwide. Traditional and novel therapeutic approaches …

[HTML][HTML] Cubosomes-assisted transdermal delivery of doxorubicin and indocyanine green for chemo-photothermal combination therapy of melanoma

Z Chen, Q Huang, Y Song, X Feng, L Zeng, Z Liu… - Biomedicine & …, 2023 - Elsevier
Melanoma is a highly aggressive form of skin cancer with limited therapeutic options.
Chemo-photothermal combination therapy has demonstrated potential for effectively treating …

[HTML][HTML] SIRT7 orchestrates melanoma progression by simultaneously promoting cell survival and immune evasion via UPR activation

X Yi, H Wang, Y Yang, H Wang, H Zhang… - … and Targeted Therapy, 2023 - nature.com
Melanoma is the most lethal type of skin cancer, originating from the malignant
transformation of melanocyte. While the development of targeted therapy and …

Kuwanon H inhibits melanoma growth through cytotoxic endoplasmic reticulum stress and impaired autophagy flux

X Hu, G Pan, J Luo, X Gao, Y Mu, Z Wang… - Journal of Agricultural …, 2023 - ACS Publications
Although great progress has been made recently in targeted and immune-based therapies,
additional treatments are needed for most melanoma patients due to acquired …