RIP1 (receptor-interacting protein kinase 1) is an important component of TNF-α signaling
that contributes to various pathological effects. Here, we revealed new potential roles of …

It is well known that the enzyme catalyzes the first step of branched-chain amino acid
(BCAA) catabolism is branched-chain amino transferase (BCAT), which is involved in the …

Despite immune checkpoint inhibitors (ICIs) have shown the greatest success in melanoma
treatment, only a subset of melanoma patients responds well to ICIs. Thus, identifying …

Interventions in gene regulatory networks (GRNs) aim to restore normal functions of cells
experiencing abnormal behavior, such as uncontrolled cell proliferation. The dynamic …

The induction of cuproptosis, a recently identified form of copper‐dependent immunogenic
cell death, is a promising approach for antitumor therapy. However, sufficient accumulation …

Increasing evidence has highlighted the critical functions of immunogenic cell death (ICD)
within many tumors. However, the therapeutic possibilities and mechanism of utilizing ICD in …

Macroautophagy, hereafter referred to as autophagy, represents a highly conserved
catabolic process that maintains cellular homeostasis. At present, the role of autophagy in …

Tumor angiogenesis is critical for tumor metastasis by providing oxygen, nutrients, and
metastatic pathways. As a potential anti‐angiogenic agent, Dihydroartemisinin (DHA) can …

Simple Summary Melanoma has the highest mortality rate of all skin cancers and its
prognosis is worsened by metastasis to the brain. Before discovering new treatments for …

Melanoma continues to be a leading cause of mortality among skin cancers. Despite
advancements in targeted therapy, patients frequently develop resistance, leading to …