Phytochemical and biological characterization of aqueous extract of Vassobia breviflora on proliferation and viability of melanoma cells: involvement of purinergic …

AR Viana, NB Bottari, VR Oviedo, D Santos… - Journal of Toxicology …, 2023 - Taylor & Francis
Vassobia breviflora belongs to the Solanaceae family, possessing biological activity against
tumor cells and is a promising alternative for therapy. The aim of this investigation was to …

[HTML][HTML] PAK1 and therapy resistance in melanoma

JV Kichina, A Maslov, ES Kandel - Cells, 2023 - mdpi.com
Malignant melanoma claims more lives than any other skin malignancy. While primary
melanomas are usually cured via surgical excision, the metastatic form of the disease …

Multifunctional near-infrared dye IR-817 encapsulated in albumin nanoparticles for enhanced imaging and photothermal therapy in melanoma

J Wang, H Liao, J Ban, S Li, X Xiong, Q He… - International Journal …, 2023 - Taylor & Francis
Background Near-infrared cyanine dyes have high sensitivity and spatial resolution imaging
capabilities, but they also have unavoidable drawbacks such as photobleaching, low water …

[HTML][HTML] High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders

GV Mkrtchyan, A Veviorskiy, E Izumchenko… - Cell Death & …, 2022 - nature.com
Multiple cancer types have limited targeted therapeutic options, in part due to incomplete
understanding of the molecular processes underlying tumorigenesis and significant intra …

Prosopis juliflora (Sw.) DC phytochemicals induce apoptosis and inhibit cell proliferation signaling pathways, EMT, migration, invasion, angiogenesis and stem cell …

J Choudhari, R Nimma, SK Nimal, SKT Venkata… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Prosopis juliflora (Sw.), DC is a xerophytic plant
species that extensively grow in Asia, Africa, Australia, and Brazil. From ancient time P …

[HTML][HTML] The molecular perspective on the development of melanoma and genome engineering of T-cells in targeting therapy

F Hajibabaie, N Abedpoor, SH Javanmard… - Environmental …, 2023 - Elsevier
Melanoma, an aggressive malignant tumor originating from melanocytes in humans, is on
the rise globally, with limited non-surgical treatment options available. Recent …

[HTML][HTML] Is Insulin Receptor Substrate4 (IRS4) a platform involved in the activation of several oncogenes?

LG Guijarro, FJ Justo Bermejo, DL Boaru… - Cancers, 2023 - mdpi.com
Simple Summary IRS4 (insulin receptor substrate4) belongs to a family of intracellular
proteins that include IRS1 and IRS2 and whose physiological function is to transmit the …

[HTML][HTML] Effect of polymorphisms in the 5'-flanking sequence of MC1R on feather color in Taihang chickens

Y Fan, X Wu, Y Li, H Han, Y Zhang, J Yang, Y Liu - Poultry Science, 2022 - Elsevier
ABSTRACT MC1R plays an important role in the regulation of the formation, transfer, and
deposition of melanin in animals and is important for determining coat color. Many studies …

[HTML][HTML] CAR NK cell therapy for the treatment of metastatic melanoma: Potential & prospects

W Hibler, G Merlino, Y Yu - Cells, 2023 - mdpi.com
Melanoma is among the most lethal forms of cancer, accounting for 80% of deaths despite
comprising just 5% of skin cancer cases. Treatment options remain limited due to the genetic …

[HTML][HTML] Liver metastasis in uveal melanoma—Treatment options and clinical outcome

S Kaštelan, DM Zimak, M Ivanković… - Frontiers in bioscience …, 2022 - imrpress.com
Uveal melanoma (UM) is the most prevalent primary intraocular malignancy in adults with a
stable incidence rate between five and seven cases per million in Europe and the United …