Phytochemical and biological characterization of aqueous extract of Vassobia breviflora on proliferation and viability of melanoma cells: involvement of purinergic …
AR Viana, NB Bottari, VR Oviedo, D Santos… - Journal of Toxicology …, 2023 - Taylor & Francis
Vassobia breviflora belongs to the Solanaceae family, possessing biological activity against
tumor cells and is a promising alternative for therapy. The aim of this investigation was to …
tumor cells and is a promising alternative for therapy. The aim of this investigation was to …
[HTML][HTML] PAK1 and therapy resistance in melanoma
JV Kichina, A Maslov, ES Kandel - Cells, 2023 - mdpi.com
Malignant melanoma claims more lives than any other skin malignancy. While primary
melanomas are usually cured via surgical excision, the metastatic form of the disease …
melanomas are usually cured via surgical excision, the metastatic form of the disease …
Multifunctional near-infrared dye IR-817 encapsulated in albumin nanoparticles for enhanced imaging and photothermal therapy in melanoma
J Wang, H Liao, J Ban, S Li, X Xiong, Q He… - International Journal …, 2023 - Taylor & Francis
Background Near-infrared cyanine dyes have high sensitivity and spatial resolution imaging
capabilities, but they also have unavoidable drawbacks such as photobleaching, low water …
capabilities, but they also have unavoidable drawbacks such as photobleaching, low water …
[HTML][HTML] High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders
Multiple cancer types have limited targeted therapeutic options, in part due to incomplete
understanding of the molecular processes underlying tumorigenesis and significant intra …
understanding of the molecular processes underlying tumorigenesis and significant intra …
Prosopis juliflora (Sw.) DC phytochemicals induce apoptosis and inhibit cell proliferation signaling pathways, EMT, migration, invasion, angiogenesis and stem cell …
J Choudhari, R Nimma, SK Nimal, SKT Venkata… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Prosopis juliflora (Sw.), DC is a xerophytic plant
species that extensively grow in Asia, Africa, Australia, and Brazil. From ancient time P …
species that extensively grow in Asia, Africa, Australia, and Brazil. From ancient time P …
[HTML][HTML] The molecular perspective on the development of melanoma and genome engineering of T-cells in targeting therapy
F Hajibabaie, N Abedpoor, SH Javanmard… - Environmental …, 2023 - Elsevier
Melanoma, an aggressive malignant tumor originating from melanocytes in humans, is on
the rise globally, with limited non-surgical treatment options available. Recent …
the rise globally, with limited non-surgical treatment options available. Recent …
[HTML][HTML] Is Insulin Receptor Substrate4 (IRS4) a platform involved in the activation of several oncogenes?
LG Guijarro, FJ Justo Bermejo, DL Boaru… - Cancers, 2023 - mdpi.com
Simple Summary IRS4 (insulin receptor substrate4) belongs to a family of intracellular
proteins that include IRS1 and IRS2 and whose physiological function is to transmit the …
proteins that include IRS1 and IRS2 and whose physiological function is to transmit the …
[HTML][HTML] Effect of polymorphisms in the 5'-flanking sequence of MC1R on feather color in Taihang chickens
Y Fan, X Wu, Y Li, H Han, Y Zhang, J Yang, Y Liu - Poultry Science, 2022 - Elsevier
ABSTRACT MC1R plays an important role in the regulation of the formation, transfer, and
deposition of melanin in animals and is important for determining coat color. Many studies …
deposition of melanin in animals and is important for determining coat color. Many studies …
[HTML][HTML] CAR NK cell therapy for the treatment of metastatic melanoma: Potential & prospects
Melanoma is among the most lethal forms of cancer, accounting for 80% of deaths despite
comprising just 5% of skin cancer cases. Treatment options remain limited due to the genetic …
comprising just 5% of skin cancer cases. Treatment options remain limited due to the genetic …
[HTML][HTML] Liver metastasis in uveal melanoma—Treatment options and clinical outcome
S Kaštelan, DM Zimak, M Ivanković… - Frontiers in bioscience …, 2022 - imrpress.com
Uveal melanoma (UM) is the most prevalent primary intraocular malignancy in adults with a
stable incidence rate between five and seven cases per million in Europe and the United …
stable incidence rate between five and seven cases per million in Europe and the United …