Resistance to MAPK inhibitors (MAPKi), the main cause of relapse in BRAF-mutant
melanoma, is associated with the production of alternative BRAF mRNA isoforms (altBRAFs) …

Melanoma is a highly aggressive tumor derived from melanocytes. In recent years, the
incidence and mortality of melanoma have gradually increased, seriously threatening …

Malignant melanoma (MM) is an extremely aggressive and fatal form of skin cancer that
primarily affects the bottom layer of the epidermis and is associated with poor clinical …

(1) Malignant melanomas are dangerous skin cancers, and the treatment of melanomas with
various cytostatic drugs often causes side effects and after their prolonged use resistance to …

The dysregulation of branched‐chain amino acid (BCAA) metabolism and related enzymes
has been greatly implicated in the progression of multiple types of cancer, whereas remains …

Cuproptosis, a recently discovered copper‐dependent cell death, presents significant
potential for the development of copper‐based nanoparticles to induce cuproptosis in …

Leonurus japonicus Houtt is an important anti-skin pigmentation herb used in traditional
Chinese medicine. However, the molecular basis for this activity is complex and not fully …

Anoikis is a unique form of apoptosis associated with vascularization and distant metastasis
in cancer. Eliminating anoikis resistance in tumor cells could be a promising target for …

Macroautophagy/autophagy has previously been regarded as simply a way for cells to deal
with nutrient emergency. But explosive work in the last 15 years has given increasingly new …

Simple Summary The unique properties of invariant natural killer T (iNKT) cells make them
an attractive candidate for cancer-adoptive immunotherapy. However, despite their potential …