Emerging dimensions of autophagy in melanoma
Macroautophagy/autophagy has previously been regarded as simply a way for cells to deal
with nutrient emergency. But explosive work in the last 15 years has given increasingly new …
with nutrient emergency. But explosive work in the last 15 years has given increasingly new …
[HTML][HTML] Melanoma Cells Inhibit iNKT Cell Functions via PGE2 and IDO1
E Torre, G Pinton, G Lombardi, S Fallarini - Cancers, 2023 - mdpi.com
Simple Summary The unique properties of invariant natural killer T (iNKT) cells make them
an attractive candidate for cancer-adoptive immunotherapy. However, despite their potential …
an attractive candidate for cancer-adoptive immunotherapy. However, despite their potential …
[HTML][HTML] RARRES1 identified by comprehensive bioinformatic analysis and experimental validation as a promising biomarker in Skin Cutaneous Melanoma
M Liu, R Bai, G Zhang, X Liu, Z Wang, K He, X Gan… - Scientific Reports, 2024 - nature.com
Skin cutaneous melanoma (SKCM) is a highly malignant form of skin cancer, known for its
unfavorable prognosis and elevated mortality rate. RARRES1, a gene responsive to retinoic …
unfavorable prognosis and elevated mortality rate. RARRES1, a gene responsive to retinoic …
[HTML][HTML] Can Whole-body baseline CT radiomics add information to the prediction of best response, progression-free survival, and overall survival of stage IV …
F Peisen, A Gerken, A Hering, I Dahm, K Nikolaou… - Diagnostics, 2023 - mdpi.com
Background: The aim of this study was to investigate whether the combination of radiomics
and clinical parameters in a machine-learning model offers additive information compared …
and clinical parameters in a machine-learning model offers additive information compared …
[HTML][HTML] Diagnosing cutaneous melanocytic tumors in the molecular era: updates and review of literature
C Huang, TWS Lau, BR Smoller - Dermatopathology, 2024 - mdpi.com
Over the past decade, molecular and genomic discoveries have experienced
unprecedented growth, fundamentally reshaping our comprehension of melanocytic tumors …
unprecedented growth, fundamentally reshaping our comprehension of melanocytic tumors …
[HTML][HTML] Development and validation of a novel T cell proliferation-related prognostic model for predicting survival and immunotherapy benefits in melanoma
J Chen, D Wang, S Chan, Q Yang, C Wang… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Background: T cell plays a crucial role in the occurrence and progression of Skin cutaneous
melanoma (SKCM). This research aims to identify the actions of T cell proliferation-related …
melanoma (SKCM). This research aims to identify the actions of T cell proliferation-related …
The Circadian Clock Component RORA Increases Immunosurveillance in Melanoma by Inhibiting PD-L1 Expression
D Liu, B Wei, L Liang, Y Sheng, S Sun, X Sun, M Li… - Cancer Research, 2024 - AACR
Circadian clock perturbation frequently occurs in cancer and facilitates tumor progression by
regulating malignant growth and shaping the immune microenvironment. Emerging …
regulating malignant growth and shaping the immune microenvironment. Emerging …
Unveiling the potential of inorganic nanoarchitecture-mediated photothermal therapy: An illustration on melanoma
A Hedaoo, P Khairnar, G Vambhurkar… - European Polymer …, 2024 - Elsevier
Melanoma is an invasive and malignant type of skin cancer characterized by its highly
metastatic nature and resistance to conventional therapies. In recent years, photothermal …
metastatic nature and resistance to conventional therapies. In recent years, photothermal …
[HTML][HTML] MiR126-targeted-nanoparticles combined with PI3K/AKT inhibitor as a new strategy to overcome melanoma resistance
MB Arasi, G De Luca, L Chronopoulou, F Pedini… - Molecular Therapy, 2024 - cell.com
Metastatic melanoma poses significant challenges as a highly lethal disease. Despite the
success of molecular targeting using BRAF V600E inhibitors (BRAFis) and immunotherapy …
success of molecular targeting using BRAF V600E inhibitors (BRAFis) and immunotherapy …
[HTML][HTML] Development of Recombinant Oncolytic rVSV-mIL12-mGMCSF for Cancer Immunotherapy
A Ryapolova, E Minskaia, N Gasanov, V Moroz… - International Journal of …, 2023 - mdpi.com
Anti-cancer therapy based on oncolytic viruses (OVs) is a targeted approach that takes
advantage of OVs' ability to selectively infect and replicate in tumor cells, activate the host …
advantage of OVs' ability to selectively infect and replicate in tumor cells, activate the host …