Antimicrobial resistance: a growing serious threat for global public health

MA Salam, MY Al-Amin, MT Salam, JS Pawar, N Akhter… - Healthcare, 2023 - mdpi.com
Antibiotics are among the most important discoveries of the 20th century, having saved
millions of lives from infectious diseases. Microbes have developed acquired antimicrobial …

Fighting antibiotic resistance—strategies and (pre) clinical developments to find new antibacterials

S Walesch, J Birkelbach, G Jézéquel, FPJ Haeckl… - EMBO …, 2023 - embopress.org
Antibacterial resistance is one of the greatest threats to human health. The development of
new therapeutics against bacterial pathogens has slowed drastically since the approvals of …

Origin of antibiotics and antibiotic resistance, and their impacts on drug development: A narrative review

G Muteeb, MT Rehman, M Shahwan, M Aatif - Pharmaceuticals, 2023 - mdpi.com
Antibiotics have revolutionized medicine, saving countless lives since their discovery in the
early 20th century. However, the origin of antibiotics is now overshadowed by the alarming …

Cationic polysaccharide conjugates as antibiotic adjuvants resensitize multidrug‐resistant bacteria and prevent resistance

S Mu, Y Zhu, Y Wang, S Qu, Y Huang… - Advanced …, 2022 - Wiley Online Library
In recent years, traditional antibiotic efficacy has rapidly diminished due to the advent of
multidrug‐resistant (MDR) bacteria, which poses severe threat to human life and globalized …

2 days versus 5 days of postoperative antibiotics for complex appendicitis: a pragmatic, open-label, multicentre, non-inferiority randomised trial

EML de Wijkerslooth, EJG Boerma, CC van Rossem… - The Lancet, 2023 - thelancet.com
Background The appropriate duration of postoperative antibiotics for complex appendicitis is
unclear. The increasing global threat of antimicrobial resistance warrants restrictive …

The Challenge of overcoming antibiotic resistance in carbapenem-resistant Gram-negative bacteria:“Attack on Titan”

G Mancuso, S De Gaetano, A Midiri, S Zummo… - Microorganisms, 2023 - mdpi.com
The global burden of bacterial resistance remains one of the most serious public health
concerns. Infections caused by multidrug-resistant (MDR) bacteria in critically ill patients …

A focused insight into thyme: Biological, chemical, and therapeutic properties of an indigenous Mediterranean herb

D Hammoudi Halat, M Krayem, S Khaled, S Younes - Nutrients, 2022 - mdpi.com
A perennial wild shrub from the Lamiaceae family and native to the Mediterranean region,
thyme is considered an important wild edible plant studied for centuries for its unique …

Pathogen‐Targeting Bimetallic Nanozymes as Ultrasonic‐Augmented ROS Generator against Multidrug Resistant Bacterial Infection

H Yao, R Zhou, J Wang, Y Wei, S Li… - Advanced …, 2023 - Wiley Online Library
Clinical treatment of multidrug resistant (MDR) pathogens‐induced infection is emerging as
a growing challenge in global public health due to the limited selection of clinically available …

Phytochemicals as antimicrobials: prospecting Himalayan medicinal plants as source of alternate medicine to combat antimicrobial resistance

MV Ashraf, S Pant, MAH Khan, AA Shah, S Siddiqui… - Pharmaceuticals, 2023 - mdpi.com
Among all available antimicrobials, antibiotics hold a prime position in the treatment of
infectious diseases. However, the emergence of antimicrobial resistance (AMR) has posed a …

[HTML][HTML] Recent development in the sustainable remediation of antibiotics: a review

KK Sodhi, CK Singh - Total Environment Research Themes, 2022 - Elsevier
Antibiotics are identified as an emerging contaminant due to their persistence in the
environment. Antibiotics, due to their accumulation in freshwater sources and wastewater …