Mechanism of Efferocytosis in Determining Ischaemic Stroke Resolution—Diving into Microglia/Macrophage Functions and Therapeutic Modality

XD Xie, SS Dong, RJ Liu, LL Shi, T Zhu - Molecular Neurobiology, 2024 - Springer
After ischaemic cerebral vascular injury, efferocytosis—a process known as the efficient
clearance of apoptotic cells (ACs) by various phagocytes in both physiological and …

Efferocytosis and Bone Dynamics

L Batoon, JR Hawse, LK McCauley… - Current osteoporosis …, 2024 - Springer
Abstract Purpose of Review This review summarizes the recently published scientific
evidence regarding the role of efferocytosis in bone dynamics and skeletal health. Recent …

Design, synthesis, in vitro and in vivo biological evaluation of pterostilbene derivatives for anti-inflammation therapy

L Chen, K Wang, X Liu, L Wang, H Zou… - Journal of Enzyme …, 2024 - Taylor & Francis
Pterostilbene (PST) is a naturally derived stilbene compound in grapes, blueberries, and
other fruits. It is also a natural dietary compound with a wide range of biological activities …

Efferocytosis in dendritic cells: an overlooked immunoregulatory process

Y Ma, T Jiang, X Zhu, Y Xu, K Wan, T Zhang… - Frontiers in …, 2024 - frontiersin.org
Efferocytosis, the process of engulfing and removing apoptotic cells, plays an essential role
in preserving tissue health and averting undue inflammation. While macrophages are …

IL-17A/IL-17RA interaction blockade sensitizes synovial macrophages to efferocytosis and PD-L1 signaling via rewiring STAT-3/ADAM17/MERTK axis in rheumatoid …

S Samarpita, S Srivastava, M Srikanth, AM Jose… - International …, 2024 - Elsevier
Defective clearance of apoptotic cells due to impaired efferocytosis sustains error in self-
tolerance that exacerbates rheumatoid arthritis (RA). However, the molecular determinant …

[引用][C] Phagocytic clearance of dying cells and its implications

KS Ravichandran - Immunological Reviews, 2023 - Wiley Online Library
It is estimated that an average adult human turns over roughly 330±20 billion cells every day
as part of healthy living. 1, 2 This translates to 0.4% of our body mass. Such a large number …