Dynamic epimarks in sex-related genes predict gonad phenotype in the European sea bass, a fish with mixed genetic and environmental sex determination

D Anastasiadi, M Vandeputte, N Sanchez-Baizan… - Epigenetics, 2018 - Taylor & Francis
The integration of genomic and environmental influences into methylation patterns to bring
about a phenotype is of central interest in developmental epigenetics, but many details are …

Characterization of Genetic and Epigenetic Variation in Sperm and Red Blood Cells from Adult Hatchery and Natural-Origin Steelhead, Oncorhynchus mykiss

MR Gavery, KM Nichols, GW Goetz… - G3: Genes …, 2018 - academic.oup.com
While the goal of most conservation hatchery programs is to produce fish that are genetically
and phenotypically indistinguishable from the wild stocks they aim to restore, there is …

Regenerating zebrafish fin epigenome is characterized by stable lineage-specific DNA methylation and dynamic chromatin accessibility

HJ Lee, Y Hou, Y Chen, ZZ Dailey, A Riddihough… - Genome biology, 2020 - Springer
Background Zebrafish can faithfully regenerate injured fins through the formation of a
blastema, a mass of proliferative cells that can grow and develop into the lost body part. After …

Evolutionary conservation of embryonic DNA methylome remodelling in distantly related teleost species

SE Ross, J Vázquez-Marín, KRB Gert… - Nucleic Acids …, 2023 - academic.oup.com
Methylation of cytosines in the CG context (mCG) is the most abundant DNA modification in
vertebrates that plays crucial roles in cellular differentiation and identity. After fertilization …

Embryonic transcription is controlled by maternally defined chromatin state

S Hontelez, I Van Kruijsbergen, G Georgiou… - Nature …, 2015 - nature.com
Histone-modifying enzymes are required for cell identity and lineage commitment, however
little is known about the regulatory origins of the epigenome during embryonic development …

Harnessing the power of multi‐omics data for predicting climate change response

KKS Layton, IR Bradbury - Journal of Animal Ecology, 2022 - Wiley Online Library
Predicting how species will respond to future climate change is of central importance in the
midst of the global biodiversity crisis, and recent work has demonstrated the utility of …

Zebrafish as a model to study the role of DNA methylation in environmental toxicology

JH Kamstra, P Aleström, JM Kooter, J Legler - Environmental Science and …, 2015 - Springer
Environmental epigenetics is a rapidly growing field which studies the effects of
environmental factors such as nutrition, stress, and exposure to compounds on epigenetic …

The BIG Data Center: from deposition to integration to translation

BIG Data Center Members - Nucleic acids research, 2017 - academic.oup.com
Biological data are generated at unprecedentedly exponential rates, posing considerable
challenges in big data deposition, integration and translation. The BIG Data Center …

Paternal ethanol exposure and behavioral abnormities in offspring: associated alterations in imprinted gene methylation

F Liang, L Diao, J Liu, N Jiang, J Zhang, H Wang… - …, 2014 - Elsevier
Research confirms that maternal ethanol (EtOH) exposure can induce physical and mental
disorders in offspring, yet the effect of paternal ethanol exposure on offspring is unclear …

The genetics of Crohn's disease and ulcerative colitis – status quo and beyond

D Ellinghaus, J Bethune, BS Petersen… - Scandinavian journal of …, 2015 - Taylor & Francis
The two major subtypes of inflammatory bowel disease (IBD), ulcerative colitis (UC, MIM#
191390) and Crohn's disease (CD, MIM# 266600), are chronic relapsing-remitting …