Dietary polyphenols and their role in oxidative stress-induced human diseases: Insights into protective effects, antioxidant potentials and mechanism (s) of action
Dietary polyphenols including phenolic acids, flavonoids, catechins, tannins, lignans,
stilbenes, and anthocyanidins are widely found in grains, cereals, pulses, vegetables …
stilbenes, and anthocyanidins are widely found in grains, cereals, pulses, vegetables …
Chalcone derivatives: role in anticancer therapy
Y Ouyang, J Li, X Chen, X Fu, S Sun, Q Wu - Biomolecules, 2021 - mdpi.com
Chalcones (1, 3-diaryl-2-propen-1-ones) are precursors for flavonoids and isoflavonoids,
which are common simple chemical scaffolds found in many naturally occurring compounds …
which are common simple chemical scaffolds found in many naturally occurring compounds …
Ethnobotany and the role of plant natural products in antibiotic drug discovery
The crisis of antibiotic resistance necessitates creative and innovative approaches, from
chemical identification and analysis to the assessment of bioactivity. Plant natural products …
chemical identification and analysis to the assessment of bioactivity. Plant natural products …
Pharmacological properties of chalcones: a review of preclinical including molecular mechanisms and clinical evidence
Chalcones are among the leading bioactive flavonoids with a therapeutic potential
implicated to an array of bioactivities investigated by a series of preclinical and clinical …
implicated to an array of bioactivities investigated by a series of preclinical and clinical …
Chalcone synthesis, properties and medicinal applications: a review
A Rammohan, JS Reddy, G Sravya, CN Rao… - Environmental …, 2020 - Springer
Chalcone is an aromatic ketone that forms the central core of many important biological
compounds, which are known as chalcones. Chalcones are the biogenetic precursors of …
compounds, which are known as chalcones. Chalcones are the biogenetic precursors of …
Chalcone scaffolds, bioprecursors of flavonoids: Chemistry, bioactivities, and pharmacokinetics
Chalcones are secondary metabolites belonging to the flavonoid (C6-C3-C6 system) family
that are ubiquitous in edible and medicinal plants, and they are bioprecursors of plant …
that are ubiquitous in edible and medicinal plants, and they are bioprecursors of plant …
A comprehensive review of monoamine oxidase inhibitors as Anti-Alzheimer's disease agents: A review
Monoamine oxidases (MAO-A and MAO-B) are mammalian flavoenzyme, which catalyze the
oxidative deamination of several neurotransmitters like norepinephrine, dopamine, tyramine …
oxidative deamination of several neurotransmitters like norepinephrine, dopamine, tyramine …
Non-steroidal anti-inflammatory drugs: Recent advances in the use of synthetic COX-2 inhibitors
M Ahmadi, S Bekeschus, KD Weltmann… - RSC Medicinal …, 2022 - pubs.rsc.org
Cyclooxygenase (COX) enzymes comprise COX-1 and COX-2 isoforms and are responsible
for prostaglandin production. Prostaglandins have critical roles in the inflammation pathway …
for prostaglandin production. Prostaglandins have critical roles in the inflammation pathway …
Induction of pyroptosis and its implications in cancer management
YY Wang, XL Liu, R Zhao - Frontiers in oncology, 2019 - frontiersin.org
Pyroptosis is a gasdermins mediated programmed cell death, which has been widely
studied in inflammatory disease models. Recently, there are growing evidences that …
studied in inflammatory disease models. Recently, there are growing evidences that …
Natural product derived privileged scaffolds in drug discovery
EK Davison, MA Brimble - Current opinion in chemical biology, 2019 - Elsevier
The biological activity and structural diversity of natural products are unsurpassed by any
available synthetic screening libraries. As such, these privileged scaffolds serve as …
available synthetic screening libraries. As such, these privileged scaffolds serve as …