[HTML][HTML] Immunological properties of gold nanoparticles

LA Dykman, NG Khlebtsov - Chemical science, 2017 - pubs.rsc.org
In the past decade, gold nanoparticles have attracted strong interest from the
nanobiotechnological community owing to the significant progress made in robust and easy …

Gold nanoparticles for preparation of antibodies and vaccines against infectious diseases

LA Dykman - Expert review of vaccines, 2020 - Taylor & Francis
Introduction Vaccination remains very effective in stimulating protective immune responses
against infections. An important task in antibody and vaccine preparation is to choose an …

siRNAs: applications in functional genomics and potential as therapeutics

Y Dorsett, T Tuschl - Nature reviews Drug discovery, 2004 - nature.com
Molecules that can specifically silence gene expression are powerful research tools. Much
effort has been put into the development of such molecules and has resulted in the creation …

Uptake of engineered gold nanoparticles into mammalian cells

LA Dykman, NG Khlebtsov - Chemical reviews, 2014 - ACS Publications
In the past decade, mammalian cells have increasingly encountered gold nanoparticles
(GNPs), owing to the active development of nanomedicine. 1− 3 GNPs have been more and …

[HTML][HTML] Progress towards in vivo use of siRNAs

MA Behlke - Molecular Therapy, 2006 - cell.com
RNA interference (RNAi) has become the method of choice to suppress gene expression in
vitro. It is also emerging as a powerful tool for in vivo research with over 90 studies …

[HTML][HTML] Aspects of phage-based vaccines for protein and epitope immunization

M Palma - Vaccines, 2023 - mdpi.com
Because vaccine development is a difficult process, this study reviews aspects of phages as
vaccine delivery vehicles through a literature search. The results demonstrated that because …

Signal transduction and cell‐type specific regulation of matrix metalloproteinase gene expression: Can MMPs be good for you?

MP Vincenti, CE Brinckerhoff - Journal of cellular physiology, 2007 - Wiley Online Library
An abundance of literature over the past several years indicates a growing interest in the
role of matrix metalloproteinases (MMPs) in normal physiology and in disease pathology …

Systemic application of CpG‐rich DNA suppresses adaptive T cell immunity via induction of IDO

G Wingender, N Garbi, B Schumak… - European journal of …, 2006 - Wiley Online Library
CpG‐rich oligonucleotides (CpG‐ODN) bind to Toll‐like receptor 9 (TLR9) and are used as
powerful adjuvants for vaccination. Here we report that CpG‐ODN not only act as immune …

Gold nanoparticles as an adjuvant: Influence of size, shape, and technique of combination with CpG on antibody production

LA Dykman, SA Staroverov, AS Fomin… - International …, 2018 - Elsevier
Gold nanoparticles (GNPs) are advantageous as an adjuvant in the design of effective
vaccines and in the preparation of high-affinity antibodies to haptens and complete antigens …

Therapeutic anti‐tumor immunity triggered by injections of immunostimulating single‐stranded RNA

B Scheel, S Aulwurm, J Probst, L Stitz… - European journal of …, 2006 - Wiley Online Library
Stabilized synthetic RNA oligonucleotides (ORN) and protected messenger RNA (mRNA)
were recently discovered to possess an immunostimulatory capacity through their …