An insight on ophthalmic drug delivery systems: focus on polymeric biomaterials-based carriers

M Shafiq, M Rafique, Y Cui, L Pan, CW Do… - Journal of Controlled …, 2023 - Elsevier
Presently, different types of eye diseases, such as glaucoma, myopia, infection, and dry eyes
are treated with topical eye drops. However, due to ocular surface barriers, eye drops …

[HTML][HTML] Up-to-date molecular medicine strategies for management of ocular surface neovascularization

Y Yang, J Zhong, D Cui, LD Jensen - Advanced Drug Delivery Reviews, 2023 - Elsevier
Ocular surface neovascularization and its resulting pathological changes significantly alter
corneal refraction and obstruct light path to the retina, and hence is a major cause of vision …

Trimethylated chitosan-coated flexible liposomes with resveratrol for topical drug delivery to reduce blue-light-induced retinal damage

H Gu, P Chen, X Liu, Y Lian, J Xi, J Li, J Song… - International Journal of …, 2023 - Elsevier
LED-related blue-light-induced damage can cause eye diseases. However, drug delivery in
patients with ocular diseases is faced with various challenges. In this study, we developed …

Nanoceria-Mediated Cyclosporin A Delivery for Dry Eye Disease Management through Modulating Immune–Epithelial Crosstalk

W Cui, S Chen, T Hu, T Zhou, C Qiu, L Jiang… - ACS …, 2024 - ACS Publications
Dry eye disease (DED) affects a substantial worldwide population with increasing frequency.
Current single-targeting DED management is severely hindered by the existence of an …

[HTML][HTML] Light-responsive polymeric nanoparticles for retinal drug delivery: design cues, challenges and future perspectives

L Guidi, MG Cascone, E Rosellini - Heliyon, 2024 - cell.com
A multitude of sight-threatening retinal diseases, affecting hundreds of millions around the
globe, lack effective pharmacological treatments due to ocular barriers and common drug …