Macromolecular crowding affects the activity of proteins and functional macromolecular
complexes in all cells, including bacteria. Crowding, together with physicochemical …

Biomolecular condensates, formed through phase separation, are upending our
understanding in much of molecular, cell, and developmental biology. There is an urgent …

Liquid–liquid phase separation (LLPS) and the formation of membraneless organelles
(MLOs) contribute to the spatiotemporal organization of various physiological processes in …

Numerous studies indicate that reversible Nε-lysine acetylation in bacteria may play a key
role in the regulation of metabolic processes, transcription and translation, biofilm formation …

Bacterial chromosome, the nucleoid, is traditionally modeled as a rosette of DNA mega-
loops, organized around proteinaceous central scaffold by nucleoid-associated proteins …

The interplay between bacterial chromosome organization and functions such as
transcription and replication can be studied in increasing detail using novel experimental …

Microbes exhibit remarkable adaptability to environmental fluctuations. Signaling
mechanisms, such as two-component systems and secondary messengers, have long been …

The ancient, inorganic biopolymer polyphosphate (polyP) occurs in all three domains of life
and affects myriad cellular processes. An intriguing feature of polyP is its frequent proximity …

In cells that are exposed to terrestrial sunlight, the indole moiety in the side chain of
tryptophan (Trp) can suffer photo/oxidative damage (POD) by reactive oxygen species …

The bacterial chromosome is both highly supercoiled and bound by an ensemble of proteins
and RNA, causing the DNA to form a compact structure termed the nucleoid. The nucleoid …