Macrophages in atherosclerosis regression

TJ Barrett - Arteriosclerosis, thrombosis, and vascular biology, 2020 - Am Heart Assoc
Macrophages play a central role in the development of atherosclerotic cardiovascular
disease (ASCVD), which encompasses coronary artery disease, peripheral artery disease …

Regulatory T cells in embryo implantation and the immune response to pregnancy

SA Robertson, AS Care… - The Journal of clinical …, 2018 - Am Soc Clin Investig
At implantation, the embryo expresses paternally derived alloantigens and evokes
inflammation that can threaten reproductive success. To ensure a robust placenta and …

Macrophage plasticity and atherosclerosis therapy

P Lin, HH Ji, YJ Li, SD Guo - Frontiers in molecular biosciences, 2021 - frontiersin.org
Atherosclerosis is a chronic disease starting with the entry of monocytes into the
subendothelium and the subsequent differentiation into macrophages. Macrophages are the …

[HTML][HTML] Immune determinants of endometrial receptivity: a biological perspective

SA Robertson, LM Moldenhauer, ES Green, AS Care… - Fertility and sterility, 2022 - Elsevier
Immune cells are essential for endometrial receptivity to embryo implantation and early
placental development. They exert tissue-remodeling and immune regulatory roles—acting …

T-cell recruitment to the heart: friendly guests or unwelcome visitors?

RM Blanton, FJ Carrillo-Salinas… - American Journal of …, 2019 - journals.physiology.org
Myocardial inflammation can lead to lethal acute or chronic heart failure (HF). T lymphocytes
(T cells), have been reported in the inflamed heart in different etiologies of HF, and more …

Interactive effect of increased high sensitive C-reactive protein and dyslipidemia on cardiovascular diseases: a 12-year prospective cohort study

SEC Bafei, X Zhao, C Chen, J Sun, Q Zhuang… - Lipids in health and …, 2023 - Springer
Background Dyslipidemia and inflammation are significant factors for the onset of
cardiovascular diseases (CVD); however, studies regarding their interactions on the risk of …

Inflammation: a novel therapeutic target/direction in atherosclerosis

B Li, W Li, X Li, H Zhou - Current Pharmaceutical Design, 2017 - ingentaconnect.com
Over the past two decades, the viewpoint of atherosclerosis has been replaced gradually by
a lipiddriven, chronic, low-grade inflammatory disease of the arterial wall. Current treatment …

SIRT 6 reduces macrophage foam cell formation by inducing autophagy and cholesterol efflux under ox‐LDL condition

J He, G Zhang, Q Pang, C Yu, J Xiong, J Zhu… - The FEBS …, 2017 - Wiley Online Library
SIRT 6 is a pivotal regulator of lipid metabolism. It is also closely connected to
cardiovascular diseases, which are the main cause of death in diabetic patients. We …

Fisetin and its role in chronic diseases

HC Pal, RL Pearlman, F Afaq - Anti-inflammatory Nutraceuticals and …, 2016 - Springer
Chronic inflammation is a prolonged and dysregulated immune response leading to a wide
variety of physiological and pathological conditions such as neurological abnormalities …

Effects and mechanisms of Danshen-Shanzha herb-pair for atherosclerosis treatment using network pharmacology and experimental pharmacology

J Zhang, R Liang, L Wang, B Yang - Journal of ethnopharmacology, 2019 - Elsevier
Ethnopharmacological relevance The danshen (the root of Salvia miltiorrhiza Bge.)-shanzha
(the fruit of Crataegus pinnatifida Bge. var. major NE Br.)(DS) herb combination is a …