Low serum albumin: a neglected predictor in patients with cardiovascular disease

AA Manolis, TA Manolis, H Melita, DP Mikhailidis… - European Journal of …, 2022 - Elsevier
Albumin, the most abundant circulating protein in blood, is an essential protein which binds
and transports various drugs and substances, maintains the oncotic pressure of blood and …

Uric Acid in Parkinson′ s disease: what is the connection?

F Seifar, AR Dinasarapu, HA Jinnah - Movement Disorders, 2022 - Wiley Online Library
Numerous studies have linked Parkinson′ s disease (PD) with low levels of uric acid (UA).
Low UA has been associated with the risk of developing PD, and its progression and …

Metabolic communication by SGLT2 inhibition

AM Billing, YC Kim, S Gullaksen, B Schrage, J Raabe… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: SGLT2 (sodium-glucose cotransporter 2) inhibitors (SGLT2i) can protect
the kidneys and heart, but the underlying mechanism remains poorly understood …

Expert consensus for the diagnosis and treatment of patient with hyperuricemia and high cardiovascular risk: 2021 update

C Borghi, J Domienik-Karłowicz, A Tykarski… - Cardiology …, 2021 - journals.viamedica.pl
Uric acid (UA) is the end product of purine metabolism, and its concentration in blood can
increase in humans, great apes, and dalmatian dogs as a consequence of a genetic …

Update in uric acid, hypertension, and cardiovascular diseases

M Kuwabara, T Kodama, R Ae, M Kanbay… - Hypertension …, 2023 - nature.com
A direct relationship between serum uric acid levels and hypertension, cardiovascular, renal
and metabolic diseases has been reported in many basic and epidemiological studies …

Progress in optical sensors-based uric acid detection

C Ma, N Jiang, X Sun, L Kong, T Liang, X Wei… - Biosensors and …, 2023 - Elsevier
The escalating number of patients affected by various diseases, such as gout, attributed to
abnormal uric acid (UA) concentrations in body fluids, has underscored the need for rapid …

Dapagliflozin reduces uric acid concentration, an independent predictor of adverse outcomes in DAPA‐HF

K McDowell, P Welsh, KF Docherty… - European Journal of …, 2022 - Wiley Online Library
Aims Blood uric acid (UA) levels are frequently elevated in patients with heart failure and
reduced ejection fraction (HFrEF), may lead to gout and are associated with worse …

Asymptomatic hyperuricaemia in chronic kidney disease: mechanisms and clinical implications

HJ Anders, Q Li, S Steiger - Clinical Kidney Journal, 2023 - academic.oup.com
Asymptomatic hyperuricaemia (HU) is considered a pathogenic factor in multiple disease
contexts, but a causative role is only proven for the crystalline form of uric acid in gouty …

[HTML][HTML] Gout and hyperuricaemia: modifiable cardiovascular risk factors?

M Burnier - Frontiers in Cardiovascular Medicine, 2023 - frontiersin.org
Gout and hyperuricaemia are two clinical situations associated with an elevated risk of
developing cardiovascular (heart failure, myocardial infarction, stroke) and metabolic and …

Apigenin ameliorates hyperuricemia and renal injury through regulation of uric acid metabolism and JAK2/STAT3 signaling pathway

T Liu, H Gao, Y Zhang, S Wang, M Lu, X Dai, Y Liu… - Pharmaceuticals, 2022 - mdpi.com
Hyperuricemia (HUA) is a kind of metabolic disease with high incidence that still needs new
countermeasures. Apigenin has uric-lowering and kidney-protective activities, but how …