Cardiovascular Risk in Patients With Takayasu Arteritis Directly Correlates With Diastolic Dysfunction and Inflammatory Cell Infiltration in the Vessel Wall: A Clinical, ex vivo and …

S Cicco, V Desantis, A Vacca, G Cazzato… - Frontiers in …, 2022 - frontiersin.org
Background Takayasu Arteritis (TAK) increases vascular stiffness and arterial resistance.
Atherosclerosis leads to similar changes. We investigated possible differences in …

Untangling the relationship between bempedoic acid and gout: results from a systematic literature review

A Alunno, F Carubbi, E Campanozzi… - Frontiers in …, 2023 - frontiersin.org
Background Bempedoic acid (BA) is a small-molecule first-in-class of inhibitor of ATP citrate
lyase that significantly lowers low-density lipoproteins cholesterol (LDL-c) in statin-intolerant …

[HTML][HTML] Relationship between serum uric acid and hypertension in the general US population aged 20 years and older: a cross-sectional study based on NHANES …

Y Wang, Y Ouyang, Y Zhang - Medicine, 2023 - journals.lww.com
The aim of this study was to investigate the association between serum uric acid (UA) levels
and hypertension in American individuals 20 years of age and older. We used continuous …

Label-Free Electrochemical Sensing Using Glassy Carbon Electrodes Modified with Multiwalled-Carbon Nanotubes Non-Covalently Functionalized with Human …

ML Mujica, A Tamborelli, P Dalmasso, G Rivas - Chemosensors, 2023 - mdpi.com
This work reports new analytical applications of glassy carbon electrodes (GCE) modified
with a nanohybrid obtained by non-covalent functionalization of multi-walled carbon …

The uric acid/HDL-C ratio may predict significant coronary stenosis in moderate left main coronary artery lesions: an intravascular ultrasonography study

ÖF Demir, A Arslan, M Kınık, B Şensoy… - Lipids in Health and …, 2024 - Springer
Background There may be severe difficulties in determining the severity of LMCA (left main
coronary artery) lesions. The use of intravascular ultrasound (IVUS) facilitates decisions …

[HTML][HTML] Wild-type Escherichia coli Nissle 1917 improves hyperuricemia by anaerobically degrading uric acid and maintaining gut microbiota profile of mice

Y Sun, D Xu, G Zhang, W Wu, Y Ma, W Kong… - Journal of Functional …, 2024 - Elsevier
Hyperuricemia is an important metabolic disease of humans. Limited clinical drugs such as
allopurinol can alleviate hyperuricemia. Wild-type Escherichia coli Nissle 1917 (EcN) has …

TMEM16F mediated phosphatidylserine exposure and microparticle release on erythrocyte contribute to hypercoagulable state in hyperuricemia

M Yan, M Xu, Z Li, Y An, Z Wang, S Li, Y Chen… - Blood Cells, Molecules …, 2022 - Elsevier
The link between hyperuricemia (HUA) and the risk of venous thromboembolism (VTE) has
been well established. However, the mechanisms of thrombus generation and the effect of …

Canagliflozin independently reduced plasma volume from conventional diuretics in patients with type 2 diabetes and chronic heart failure: a subanalysis of the …

K Shiina, H Tomiyama, A Tanaka, T Imai… - Hypertension …, 2023 - nature.com
Sodium-glucose cotransporter 2 inhibitors (SGLT2is) reduce the risk of heart failure
progression and mortality rates. Moreover, osmotic diuresis induced by SGLT2 inhibition …

Population characteristics and diagnosis rate of chronic kidney disease by eGFR and proteinuria in Japanese clinical practice: an observational database study

T Tanaka, S Maruyama, N Chishima, H Akiyama… - Scientific Reports, 2024 - nature.com
Chronic kidney disease (CKD) guidelines recommend early identification and intervention to
delay the progression of CKD. The Kidney Disease: Improving Global Outcomes (KDIGO) …

Relationship between baseline and changed serum uric acid and the incidence of type 2 diabetes mellitus: a national cohort study

C Wang, J Wang, R Wan, T Yuan, L Yang… - Frontiers in Public …, 2023 - frontiersin.org
Objective To explore the correlation between baseline serum uric acid (SUA) and SUA
changes with the incidence of type 2 diabetes mellitus (T2DM) among middle-aged and …