Apolipoprotein A-IV: a multifunctional protein involved in protection against atherosclerosis and diabetes
Apolipoprotein A-IV (apoA-IV) is a lipid-binding protein, which is primarily synthesized in the
small intestine, packaged into chylomicrons, and secreted into intestinal lymph during fat …
small intestine, packaged into chylomicrons, and secreted into intestinal lymph during fat …
Apolipoproteins: metabolic role and clinical biochemistry applications
MH Dominiczak, MJ Caslake - Annals of clinical biochemistry, 2011 - journals.sagepub.com
Lipoprotein metabolism is dependent on apolipoproteins, multifunctional proteins that serve
as templates for the assembly of lipoprotein particles, maintain their structure and direct their …
as templates for the assembly of lipoprotein particles, maintain their structure and direct their …
Nutritional genomics
JM Ordovas, D Corella - Annu. Rev. Genomics Hum. Genet., 2004 - annualreviews.org
▪ Abstract Nutritional genomics has tremendous potential to change the future of dietary
guidelines and personal recommendations. Nutrigenetics will provide the basis for …
guidelines and personal recommendations. Nutrigenetics will provide the basis for …
Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides
PJ Talmud, E Hawe, S Martin, M Olivier… - Human molecular …, 2002 - academic.oup.com
Since triglycerides (TG) are a major independent risk factor for coronary heart disease,
understanding their genetic and environmental determinants is of major importance. Mouse …
understanding their genetic and environmental determinants is of major importance. Mouse …
Common gene polymorphisms and nutrition: emerging links with pathogenesis of multifactorial chronic diseases
A Loktionov - The Journal of nutritional biochemistry, 2003 - Elsevier
Rapid progress in human genome decoding has accelerated search for the role of gene
polymorphisms in the pathogenesis of complex multifactorial diseases. This review …
polymorphisms in the pathogenesis of complex multifactorial diseases. This review …
A sandwich enzyme-linked immunosorbent assay for human plasma apolipoprotein AV concentration
M Ishihara, T Kujiraoka, T Iwasaki, M Nagano… - Journal of lipid …, 2005 - ASBMB
Apolipoprotein AV (apoA-V) is a recently discovered apolipoprotein that appears to have a
role in plasma triglyceride (TG) transport. We have developed an ELISA for apoA-V using …
role in plasma triglyceride (TG) transport. We have developed an ELISA for apoA-V using …
Apolipoprotein A-IV reduces hepatic gluconeogenesis through nuclear receptor NR1D1
We showed recently that apoA-IV improves glucose homeostasis by enhancing pancreatic
insulin secretion in the presence of elevated levels of glucose. Therefore, examined whether …
insulin secretion in the presence of elevated levels of glucose. Therefore, examined whether …
Apolipoprotein AIV gene variant S347 is associated with increased risk of coronary heart disease and lower plasma apolipoprotein AIV levels
WR Wong, E Hawe, LK Li, GJ Miller, V Nicaud… - Circulation …, 2003 - Am Heart Assoc
The impact of common variants in the apolipoprotein gene cluster (APOC3-A4-A5) on
prospective coronary heart disease (CHD) risk was examined in healthy UK men. Of the …
prospective coronary heart disease (CHD) risk was examined in healthy UK men. Of the …
Cholesterol transport and beyond: Illuminating the versatile functions of HDL apolipoproteins through structural insights and functional implications
High‐density lipoproteins (HDLs) play a vital role in lipid metabolism and cardiovascular
health, as they are intricately involved in cholesterol transport and inflammation modulation …
health, as they are intricately involved in cholesterol transport and inflammation modulation …
Apolipoprotein A-IV-Deficient Mice in 129/SvJ Background Are Susceptible to Obesity and Glucose Intolerance
Apolipoprotein A-IV (apoA-IV), synthesized by enterocytes, is potentially involved in
regulating lipid absorption and metabolism, food intake, and glucose metabolism. In this …
regulating lipid absorption and metabolism, food intake, and glucose metabolism. In this …