Multi-omic and multi-view clustering algorithms: review and cancer benchmark

N Rappoport, R Shamir - Nucleic acids research, 2018 - academic.oup.com
Recent high throughput experimental methods have been used to collect large biomedical
omics datasets. Clustering of single omic datasets has proven invaluable for biological and …

Variable selection–a review and recommendations for the practicing statistician

G Heinze, C Wallisch, D Dunkler - Biometrical journal, 2018 - Wiley Online Library
Statistical models support medical research by facilitating individualized outcome
prognostication conditional on independent variables or by estimating effects of risk factors …

Dynamics of CTCF-and cohesin-mediated chromatin looping revealed by live-cell imaging

M Gabriele, HB Brandão, S Grosse-Holz, A Jha… - Science, 2022 - science.org
Animal genomes are folded into loops and topologically associating domains (TADs) by
CTCF and loop-extruding cohesins, but the live dynamics of loop formation and stability …

Determinants of COVID-19 disease severity in patients with cancer

EV Robilotti, NE Babady, PA Mead, T Rolling… - Nature medicine, 2020 - nature.com
Abstract As of 10 April 2020, New York State had 180,458 cases of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) and 9,385 reported deaths. Patients with cancer …

Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection

V Ramlall, PM Thangaraj, C Meydan, J Foox, D Butler… - Nature medicine, 2020 - nature.com
Understanding the pathophysiology of SARS-CoV-2 infection is critical for therapeutic and
public health strategies. Viral–host interactions can guide discovery of disease regulators …

[HTML][HTML] Consensus recommendations on calf-and herd-level passive immunity in dairy calves in the United States

J Lombard, N Urie, F Garry, S Godden, J Quigley… - Journal of dairy …, 2020 - Elsevier
Passive immunity in calves is evaluated or quantified by measuring serum or plasma IgG or
serum total protein within the first 7 d of age. While these measurements inform about …

Smoking, drinking, diet and physical activity—modifiable lifestyle risk factors and their associations with age to first chronic disease

R Ng, R Sutradhar, Z Yao, WP Wodchis… - International journal …, 2020 - academic.oup.com
Background This study examined the incidence of a person's first diagnosis of a selected
chronic disease, and the relationships between modifiable lifestyle risk factors and age to …

DeepSurv: personalized treatment recommender system using a Cox proportional hazards deep neural network

JL Katzman, U Shaham, A Cloninger, J Bates… - BMC medical research …, 2018 - Springer
Background Medical practitioners use survival models to explore and understand the
relationships between patients' covariates (eg clinical and genetic features) and the …

Casirivimab–Imdevimab treatment is associated with reduced rates of hospitalization among high-risk patients with mild to moderate coronavirus disease-19

RR Razonable, C Pawlowski, JC O'Horo, LL Arndt… - …, 2021 - thelancet.com
Background Real-world clinical data to support the use of casirivimab–imdevimab for the
treatment of outpatients with mild to moderate coronavirus disease-19 (COVID-19) is …

Reporting recommendations for tumor marker prognostic studies (REMARK): an abridged explanation and elaboration

W Sauerbrei, SE Taube, LM McShane… - JNCI: Journal of the …, 2018 - academic.oup.com
Abstract The Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK)
were developed to address widespread deficiencies in the reporting of such studies. The …