Postoperative atrial fibrillation: mechanisms, manifestations and management
Postoperative atrial fibrillation (POAF) complicates 20–40% of cardiac surgical procedures
and 10–20% of non-cardiac thoracic operations. Typical features include onset at 2–4 days …
and 10–20% of non-cardiac thoracic operations. Typical features include onset at 2–4 days …
Modernized classification of cardiac antiarrhythmic drugs
M Lei, L Wu, DA Terrar, CLH Huang - Circulation, 2018 - Am Heart Assoc
Background: Among his major cardiac electrophysiological contributions, Miles Vaughan
Williams (1918–2016) provided a classification of antiarrhythmic drugs that remains central …
Williams (1918–2016) provided a classification of antiarrhythmic drugs that remains central …
Cellular and molecular electrophysiology of atrial fibrillation initiation, maintenance, and progression
Atrial fibrillation (AF) is the most common clinically relevant arrhythmia and is associated
with increased morbidity and mortality. The incidence of AF is expected to continue to rise …
with increased morbidity and mortality. The incidence of AF is expected to continue to rise …
Atrial fibrillation pathophysiology: implications for management
Y Iwasaki, K Nishida, T Kato, S Nattel - Circulation, 2011 - Am Heart Assoc
Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is an important
contributor to population morbidity and mortality. An arrhythmia that is particularly common …
contributor to population morbidity and mortality. An arrhythmia that is particularly common …
Pathophysiological mechanisms of atrial fibrillation: a translational appraisal
U Schotten, S Verheule, P Kirchhof… - Physiological …, 2011 - journals.physiology.org
Atrial fibrillation (AF) is an arrhythmia that can occur as the result of numerous different
pathophysiological processes in the atria. Some aspects of the morphological and …
pathophysiological processes in the atria. Some aspects of the morphological and …
[HTML][HTML] Recent advances in the molecular pathophysiology of atrial fibrillation
Atrial fibrillation (AF) is an extremely common cardiac rhythm disorder that causes
substantial morbidity and contributes to mortality. The mechanisms underlying AF are …
substantial morbidity and contributes to mortality. The mechanisms underlying AF are …
Mechanisms of atrial fibrillation
RS Wijesurendra, B Casadei - Heart, 2019 - heart.bmj.com
Atrial fibrillation (AF) is the most common sustained arrhythmia, currently affecting over 33
million individuals worldwide, and its prevalence is expected to more than double over the …
million individuals worldwide, and its prevalence is expected to more than double over the …
[HTML][HTML] The role of reactive oxygen species in the pathophysiology of cardiovascular diseases and the clinical significance of myocardial redox
Acute and chronic excessive intracellular increase of reactive oxygen species (ROS) is
involved in the development and progression of cardiovascular diseases. ROS are by …
involved in the development and progression of cardiovascular diseases. ROS are by …
Human Atrial Action Potential and Ca2+ Model: Sinus Rhythm and Chronic Atrial Fibrillation
Rationale: Understanding atrial fibrillation (AF) requires integrated understanding of ionic
currents and Ca2+ transport in remodeled human atrium, but appropriate models are limited …
currents and Ca2+ transport in remodeled human atrium, but appropriate models are limited …
Atrial‐like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial‐selective pharmacology
HD Devalla, V Schwach, JW Ford, JT Milnes… - EMBO molecular …, 2015 - embopress.org
Drugs targeting atrial‐specific ion channels, Kv1. 5 or Kir3. 1/3.4, are being developed as
new therapeutic strategies for atrial fibrillation. However, current preclinical studies carried …
new therapeutic strategies for atrial fibrillation. However, current preclinical studies carried …