Macrophage-mediated inflammation in normal and diabetic wound healing

AE Boniakowski, AS Kimball, BN Jacobs… - The Journal of …, 2017 - journals.aai.org
The healing of cutaneous wounds is dependent on the progression through distinct, yet
overlapping phases of wound healing, including hemostasis, inflammation, proliferation, and …

The role of inflammation in venous thromboembolism

BR Branchford, SL Carpenter - Frontiers in pediatrics, 2018 - frontiersin.org
Venous thromboembolism (VTE), comprising deep vein thrombosis (DVT), and pulmonary
embolism (PE), is becoming increasingly recognized as a cause of morbidity and mortality in …

Fibrinogen and fibrin in hemostasis and thrombosis

S Kattula, JR Byrnes, AS Wolberg - … , thrombosis, and vascular …, 2017 - Am Heart Assoc
Multiple mechanisms mediate thrombin generation and consequently the thrombin
concentration present during fibrin formation. First, the levels of pro-and anticoagulants …

Thrombosis as an intravascular effector of innate immunity

B Engelmann, S Massberg - Nature Reviews Immunology, 2013 - nature.com
Thrombosis is the most frequent cause of mortality worldwide and is closely linked to
haemostasis, which is the biological mechanism that stops bleeding after the injury of blood …

The role of leukocytes in thrombosis

LL Swystun, PC Liaw - Blood, The Journal of the American …, 2016 - ashpublications.org
In recent years, the traditional view of the hemostatic system as being regulated by a
coagulation factor cascade coupled with platelet activation has been increasingly …

Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice

K Stark, V Philippi, S Stockhausen… - Blood, The Journal …, 2016 - ashpublications.org
Deep venous thrombosis (DVT) is one of the most common cardiovascular diseases, but its
pathophysiology remains incompletely understood. Although sterile inflammation has …

New insights into the mechanisms of venous thrombosis

N Mackman - The Journal of clinical investigation, 2012 - Am Soc Clin Investig
Venous thrombosis is a leading cause of morbidity and mortality in industrialized countries,
especially in the elderly. Many risk factors have been identified for venous thrombosis that …

Surgical duration and risk of venous thromboembolism

JYS Kim, N Khavanin, A Rambachan… - JAMA …, 2015 - jamanetwork.com
Importance There is a paucity of data assessing the effect of increased surgical duration on
the incidence of venous thromboembolism (VTE). Objective To examine the association …

[HTML][HTML] Immune factors in deep vein thrombosis initiation

I Budnik, A Brill - Trends in immunology, 2018 - cell.com
Deep vein thrombosis (DVT) is a major origin of morbidity and mortality. While DVT has long
been considered as blood coagulation disorder, several recent lines of evidence …

Bioprinted thrombosis-on-a-chip

YS Zhang, F Davoudi, P Walch, A Manbachi, X Luo… - Lab on a Chip, 2016 - pubs.rsc.org
Pathologic thrombosis kills more people than cancer and trauma combined; it is associated
with significant disability and morbidity, and represents a major healthcare burden. Despite …