Due to the structure of acylhydrazones both by the pharmacophore–CO–NH–N= group and
by the different substituents present in the molecules of compounds of this class, various …

The N‐acylhydrazone motif has been shown to be particularly adaptable and promising in
the area of medicinal chemistry and drug development, due to its significant biological and …

Background: For the past several decades, the presence of tuberculosis (TB) is being
remarked as the most common infectious disease leading to mortality. Objective: Hydrazone …

Tuberculosis (TB) is a major cause of mortality and illness as reported by the WHO in 2019.
The WHO report also mentioned the fact that about 10.0 million people fell ill with …

Three novel series of chalcone derivatives containing an aminoguanidine or acylhydrazone
moiety were designed, synthesized and evaluated in terms of their antibacterial, antifungal …

A series of biologically active metal complexes was yielded from the reactions of 2‐(4‐
bromophenylamino) acetohydrazide ligand (HL) with Co (II), Ni (II), Cu (II), Cd (II) chlorides …

Background: Since the last few decades, the healthcare sector is facing the problem of the
development of multidrug-resistant (MDR-TB) and extensively drug-resistant tuberculosis …

In the present work, twelve N-substituted 2-(5-nitro-thiophene)-thiosemicarbazones
derivatives (L1-12) were synthesized, characterized and their in vitro cytotoxic and …

Background: The treatment of multiple-drug-resistant tuberculosis (MDR-TB) with currently
available marketed drugs remains a global health concern. The cases of resistant …

Purpose To investigate the effect of derivatives of cinnamic acid on the proliferation of CHO-
1 and HeLa cell lines. Methods Three Acrylohydrazones (7–9) derived from cinnamic acid …