[HTML][HTML] Frailty and cytokines in preclinical models: Comparisons with humans
Chronic low-grade elevations of blood-borne cytokines/chemokines in older age tend to
associate with frailty in humans. This persistent inflammation is often called “inflammageing” …
associate with frailty in humans. This persistent inflammation is often called “inflammageing” …
[HTML][HTML] The clinical implications of bacterial pathogenesis and mucosal immunity in chronic urinary tract infection
CCY Chieng, Q Kong, NSY Liou, R Khasriya… - Mucosal …, 2023 - Elsevier
Urinary tract infections (UTIs) exert a significant health and economic cost globally.
Approximately one in four people with a previous history of UTI continue to develop …
Approximately one in four people with a previous history of UTI continue to develop …
Human umbilical cord mesenchymal stem cells ameliorate colon inflammation via modulation of gut microbiota-SCFAs-immune axis
A Liu, X Liang, W Wang, C Wang, J Song, J Guo… - Stem Cell Research & …, 2023 - Springer
Background Inflammatory bowel disease (IBD) is a global health problem in which gut
microbiota dysbiosis plays a pivotal pathogenic role. Mesenchymal stem cells (MSCs) …
microbiota dysbiosis plays a pivotal pathogenic role. Mesenchymal stem cells (MSCs) …
IL-10 negatively controls the primary T cell response of tilapia by triggering the JAK1/STAT3/SOCS3 axis that suppresses NF-κB and MAPK/ERK signaling
K Li, J Li, X Wei, J Wang, M Geng, K Ai… - The Journal of …, 2023 - journals.aai.org
The braking mechanisms to protect the host from tissue damage and inflammatory disease
caused by an overexuberant immune response are common in many T cell subsets …
caused by an overexuberant immune response are common in many T cell subsets …
Helminth antigens differentially modulate the activation of CD4+ and CD8+ T lymphocytes of convalescent COVID-19 patients in vitro
Background The coronavirus disease 2019 (COVID-19) is a respiratory disease caused by
SARS-CoV-2, a recently discovered strain of coronavirus. The virus has spread rapidly …
SARS-CoV-2, a recently discovered strain of coronavirus. The virus has spread rapidly …
Role of Serum Interleukin-6, Interleukin-1β and Interleukin-10 in Assessment of Disease Activity and Nutritional Status in Patients with Inflammatory Bowel Disease
M Godala, E Gaszyńska, K Walczak… - Journal of Clinical …, 2023 - mdpi.com
Inflammatory bowel diseases (IBD) are characterised by multifactorial and chronic
inflammation. Much attention has been paid to immune dysfunction in inflammatory bowel …
inflammation. Much attention has been paid to immune dysfunction in inflammatory bowel …
Low-intensity physical exercise decreases inflammation and joint damage in the preclinical phase of a rheumatoid arthritis murine model
SA González-Chávez, SM López-Loeza… - Biomolecules, 2023 - mdpi.com
Lifestyle modifications in preclinical Rheumatoid Arthritis (RA) could delay the ongoing
pathogenic immune processes and potentially prevent its onset. Physical exercise (PE) …
pathogenic immune processes and potentially prevent its onset. Physical exercise (PE) …
Neuroprotective effects of probiotics on anxiety-and depression-like disorders in stressed mice by modulating tryptophan metabolism and the gut microbiota
L Jia, L Xiao, Y Fu, Z Shao, Z Jing, J Yuan, Y Xie… - Food & Function, 2024 - pubs.rsc.org
Anxiety-and depression-like behaviors are commonly observed clinical features of
depression and many other mental disorders. Recent evidence has revealed the crucial role …
depression and many other mental disorders. Recent evidence has revealed the crucial role …
The prognostic significance and potential mechanism of prolyl 3‐hydroxylase 1 in hepatocellular carcinoma
C Li, L Zhang, Y Xu, D Chai, S Nan, Z Qiu… - Journal of …, 2022 - Wiley Online Library
Background. Prolyl 3‐hydroxylase 1 (P3H1) is essential for human collagen synthesis. Here,
we investigated its relevance to multiple cancers, especially hepatocellular carcinoma …
we investigated its relevance to multiple cancers, especially hepatocellular carcinoma …
Tespa1 deficiency reduces the antitumour immune response by decreasing CD8+ T cell activity in a mouse Lewis lung cancer model
Thymocyte-expressed, positive selection-associated 1 (Tespa1) is a key molecule in T-cell
development and has been linked to immune diseases. However, its role in antitumour …
development and has been linked to immune diseases. However, its role in antitumour …